TopFIND 4.0

P31314: T-cell leukemia homeobox protein 1

General Information

Protein names
- T-cell leukemia homeobox protein 1
- Homeobox protein Hox-11
- Proto-oncogene TCL-3
- T-cell leukemia/lymphoma protein 3
Gene names TLX1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P31314

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEHLGPHHLH PGHAEPISFG IDQILNSPDQ GGCMGPASRL QDGEYGLGCL VGGAYTYGGG 
        70         80         90        100        110        120 
GSAAATGAGG AGAYGTGGPG GPGGPAGGGG ACSMGPLTGS YNVNMALAGG PGPGGGGGSS 
       130        140        150        160        170        180 
GGAGALSAAG VIRVPAHRPL AGAVAHPQPL ATGLPTVPSV PAMPGVNNLT GLTFPWMESN 
       190        200        210        220        230        240 
RRYTKDRFTG HPYQNRTPPK KKKPRTSFTR LQICELEKRF HRQKYLASAE RAALAKALKM 
       250        260        270        280        290        300 
TDAQVKTWFQ NRRTKWRRQT AEEREAERQQ ANRILLQLQQ EAFQKSLAQP LPADPLCVHN 
       310        320        330    
SSLFALQNLQ PWSDDSTKIT SVTSVASACE 

Isoforms

- Isoform 2 of T-cell leukemia homeobox protein 1

Sequence View

        10         20         30         40         50         60 
MEHLGPHHLH PGHAEPISFG IDQILNSPDQ GGCMGPASRL QDGEYGLGCL VGGAYTYGGG 
        70         80         90        100        110        120 
GSAAATGAGG AGAYGTGGPG GPGGPAGGGG ACSMGPLTGS YNVNMALAGG PGPGGGGGSS 
       130        140        150        160        170        180 
GGAGALSAAG VIRVPAHRPL AGAVAHPQPL ATGLPTVPSV PAMPGVNNLT GLTFPWMESN 
       190        200        210        220        230        240 
RRYTKDRFTG HPYQNRTPPK KKKPRTSFTR LQICELEKRF HRQKYLASAE RAALAKALKM 
       250        260        270        280        290        300 
TDAQVKTWFQ NRRTKWRRQT AEEREAERQQ ANRILLQLQQ EAFQKSLAQP LPADPLCVHN 
       310        320        330    
SSLFALQNLQ PWSDDSTKIT SVTSVASACE 



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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P31314-1-unknown MEHLGP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P31314-1-unknown MEHLGP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92275

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RTKWRR 257 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt87893
    ...ASACE 330 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)