TopFIND 4.0

P31596: Excitatory amino acid transporter 2

General Information

Protein names
- Excitatory amino acid transporter 2
- GLT-1 {ECO:0000303|PubMed:11860269, ECO:0000303|PubMed:1448170}
- Sodium-dependent glutamate/aspartate transporter 2
- GLUT-R
- Solute carrier family 1 member 2
Gene names Slc1a2
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P31596

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASTEGANNM PKQVEVRMHD SHLSSEEPKH RNLGMRMCDK LGKNLLLSLT VFGVILGAVC 
        70         80         90        100        110        120 
GGLLRLAAPI HPDVVMLIAF PGDILMRMLK MLILPLIISS LITGLSGLDA KASGRLGTRA 
       130        140        150        160        170        180 
MVYYMSTTII AAVLGVILVL AIHPGNPKLK KQLGPGKKND EVSSLDAFLD LIRNLFPENL 
       190        200        210        220        230        240 
VQACFQQIQT VTKKVLVAPP SEEANTTKAV ISLLNETMNE APEETKIVIK KGLEFKDGMN 
       250        260        270        280        290        300 
VLGLIGFFIA FGIAMGKMGE QAKLMVEFFN ILNEIVMKLV IMIMWYSPLG IACLICGKII 
       310        320        330        340        350        360 
AIKDLEVVAR QLGMYMITVI VGLIIHGGIF LPLIYFVVTR KNPFSFFAGI FQAWITALGT 
       370        380        390        400        410        420 
ASSAGTLPVT FRCLEDNLGI DKRVTRFVLP VGATINMDGT ALYEAVAAIF IAQMNGVILD 
       430        440        450        460        470        480 
GGQIVTVSLT ATLASIGAAS IPSAGLVTML LILTAVGLPT EDISLLVAVD WLLDRMRTSV 
       490        500        510        520        530        540 
NVVGDSFGAG IVYHLSKSEL DTIDSQHRMH EDIEMTKTQS VYDDTKNHRE SNSNQCVYAA 
       550        560        570    
HNSVVIDECK VTLAANGKSA DCSVEEEPWK REK

Isoforms

- Isoform Glt-1A of Excitatory amino acid transporter 2

Sequence View

        10         20         30         40         50         60 
MASTEGANNM PKQVEVRMHD SHLSSEEPKH RNLGMRMCDK LGKNLLLSLT VFGVILGAVC 
        70         80         90        100        110        120 
GGLLRLAAPI HPDVVMLIAF PGDILMRMLK MLILPLIISS LITGLSGLDA KASGRLGTRA 
       130        140        150        160        170        180 
MVYYMSTTII AAVLGVILVL AIHPGNPKLK KQLGPGKKND EVSSLDAFLD LIRNLFPENL 
       190        200        210        220        230        240 
VQACFQQIQT VTKKVLVAPP SEEANTTKAV ISLLNETMNE APEETKIVIK KGLEFKDGMN 
       250        260        270        280        290        300 
VLGLIGFFIA FGIAMGKMGE QAKLMVEFFN ILNEIVMKLV IMIMWYSPLG IACLICGKII 
       310        320        330        340        350        360 
AIKDLEVVAR QLGMYMITVI VGLIIHGGIF LPLIYFVVTR KNPFSFFAGI FQAWITALGT 
       370        380        390        400        410        420 
ASSAGTLPVT FRCLEDNLGI DKRVTRFVLP VGATINMDGT ALYEAVAAIF IAQMNGVILD 
       430        440        450        460        470        480 
GGQIVTVSLT ATLASIGAAS IPSAGLVTML LILTAVGLPT EDISLLVAVD WLLDRMRTSV 
       490        500        510        520        530        540 
NVVGDSFGAG IVYHLSKSEL DTIDSQHRMH EDIEMTKTQS VYDDTKNHRE SNSNQCVYAA 
       550        560        570    
HNSVVIDECK VTLAANGKSA DCSVEEEPWK REK



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P31596-1-unknown MASTEG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...WKREK 573 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...WKREK 573 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt152507

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)