TopFIND 4.0

P31641: Sodium- and chloride-dependent taurine transporter

General Information

Protein names
- Sodium- and chloride-dependent taurine transporter
- Solute carrier family 6 member 6
Gene names SLC6A6
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P31641

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MATKEKLQCL KDFHKDILKP SPGKSPGTRP EDEAEGKPPQ REKWSSKIDF VLSVAGGFVG 
        70         80         90        100        110        120 
LGNVWRFPYL CYKNGGGAFL IPYFIFLFGS GLPVFFLEII IGQYTSEGGI TCWEKICPLF 
       130        140        150        160        170        180 
SGIGYASVVI VSLLNVYYIV ILAWATYYLF QSFQKELPWA HCNHSWNTPH CMEDTMRKNK 
       190        200        210        220        230        240 
SVWITISSTN FTSPVIEFWE RNVLSLSPGI DHPGSLKWDL ALCLLLVWLV CFFCIWKGVR 
       250        260        270        280        290        300 
STGKVVYFTA TFPFAMLLVL LVRGLTLPGA GAGIKFYLYP DITRLEDPQV WIDAGTQIFF 
       310        320        330        340        350        360 
SYAICLGAMT SLGSYNKYKY NSYRDCMLLG CLNSGTSFVS GFAIFSILGF MAQEQGVDIA 
       370        380        390        400        410        420 
DVAESGPGLA FIAYPKAVTM MPLPTFWSIL FFIMLLLLGL DSQFVEVEGQ ITSLVDLYPS 
       430        440        450        460        470        480 
FLRKGYRREI FIAFVCSISY LLGLTMVTEG GMYVFQLFDY YAASGVCLLW VAFFECFVIA 
       490        500        510        520        530        540 
WIYGGDNLYD GIEDMIGYRP GPWMKYSWAV ITPVLCVGCF IFSLVKYVPL TYNKTYVYPN 
       550        560        570        580        590        600 
WAIGLGWSLA LSSMLCVPLV IVIRLCQTEG PFLVRVKYLL TPREPNRWAV EREGATPYNS 
       610        620    
RTVMNGALVK PTHIIVETMM 

Isoforms

- Isoform 2 of Sodium- and chloride-dependent taurine transporter

Sequence View

        10         20         30         40         50         60 
MATKEKLQCL KDFHKDILKP SPGKSPGTRP EDEAEGKPPQ REKWSSKIDF VLSVAGGFVG 
        70         80         90        100        110        120 
LGNVWRFPYL CYKNGGGAFL IPYFIFLFGS GLPVFFLEII IGQYTSEGGI TCWEKICPLF 
       130        140        150        160        170        180 
SGIGYASVVI VSLLNVYYIV ILAWATYYLF QSFQKELPWA HCNHSWNTPH CMEDTMRKNK 
       190        200        210        220        230        240 
SVWITISSTN FTSPVIEFWE RNVLSLSPGI DHPGSLKWDL ALCLLLVWLV CFFCIWKGVR 
       250        260        270        280        290        300 
STGKVVYFTA TFPFAMLLVL LVRGLTLPGA GAGIKFYLYP DITRLEDPQV WIDAGTQIFF 
       310        320        330        340        350        360 
SYAICLGAMT SLGSYNKYKY NSYRDCMLLG CLNSGTSFVS GFAIFSILGF MAQEQGVDIA 
       370        380        390        400        410        420 
DVAESGPGLA FIAYPKAVTM MPLPTFWSIL FFIMLLLLGL DSQFVEVEGQ ITSLVDLYPS 
       430        440        450        460        470        480 
FLRKGYRREI FIAFVCSISY LLGLTMVTEG GMYVFQLFDY YAASGVCLLW VAFFECFVIA 
       490        500        510        520        530        540 
WIYGGDNLYD GIEDMIGYRP GPWMKYSWAV ITPVLCVGCF IFSLVKYVPL TYNKTYVYPN 
       550        560        570        580        590        600 
WAIGLGWSLA LSSMLCVPLV IVIRLCQTEG PFLVRVKYLL TPREPNRWAV EREGATPYNS 
       610        620    
RTVMNGALVK PTHIIVETMM 



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(REFRESH)

Directness:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P31641-1-unknown MATKEK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P31641-1-unknown MATKEK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88959

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IEFWER 200 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt84577
    ...VETMM 620 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)