TopFIND 4.0

P31651: Sodium- and chloride-dependent betaine transporter

General Information

Protein names
- Sodium- and chloride-dependent betaine transporter
- Na(+)/Cl(-) betaine/GABA transporter
- Sodium- and chloride-dependent GABA transporter 2
- GAT-2
- Solute carrier family 6 member 12
Gene names Slc6a12
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P31651

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDRKVAVHED GYPVVSWVPE EGEMMDQKGK DQVKDRGQWT NKMEFVLSVA GEIIGLGNVW 
        70         80         90        100        110        120 
RFPYLCYKNG GGAFFIPYFI FFFSCGIPVF FLEVALGQYS SQGSVTAWRK ICPLLQGIGM 
       130        140        150        160        170        180 
ASVVIESYLN IYYIIILAWA LFYLFSSFTW ELPWTTCTNS WNTEHCVDFL NHSSARGVSS 
       190        200        210        220        230        240 
SENFTSPVME FWERRVLGIT SGIHDLGSLR WELALCLLLA WIICYFCIWK GVKSTGKVVY 
       250        260        270        280        290        300 
FTATFPYLML IILLIRGVTL PGAYQGIVFY LKPDLLRLKD PQVWMDAGTQ IFFSFAICQG 
       310        320        330        340        350        360 
CLTALGSYNK YHNNCYRDSI ALCFLNSATS FVAGFVVFSI LGFMSQEQGI PISEVAESGP 
       370        380        390        400        410        420 
GLAFIAFPKA VTMMPLSQLW SCLFFIMLLF LGLDSQFVCM ECLVTASMDM FPQQLRKSGR 
       430        440        450        460        470        480 
RDVLILAISV LCYLMGLLLV TEGGMYIFQL FDYYASSGIC LLFLSLFEVI CIGWVYGADR 
       490        500        510        520        530        540 
FYDNVEDMIG YRPWPLVKIS WLFLTPGLCL ATFFFSLSKY TPLKYNNVYM YPSWGYSIGW 
       550        560        570        580        590        600 
LLAFSSMACV PLFIIITFLK TQGSFKKRLR RLITPDPSLP QPGRRPPQDG SSAQNCSSSP 
       610    
AKQELIAWEK ETHL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P31651-1-unknown MDRKVA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KETHL 614 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)