P31955: Amphiregulin
| Protein names | - Amphiregulin - AR - Schwannoma-derived growth factor - SDGF |
|---|---|
| Gene names | Areg |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P31955 |
4
N-termini
4
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MRTPLLPLAR SVLLLLVLGS GHYAAALELN DPSSGKGESL SGDHSAGGLE LSVGREVSTI
70 80 90 100 110 120
SEMPSGSELS TGDYDYSEEY DNEPQISGYI IDDSVRVEQV IKPKKNKTEG EKSTEKPKRK
130 140 150 160 170 180
KKGGKNGKGR RNKKKKNPCT AKFQNFCIHG ECRYIENLEV VTCNCHQDYF GERCGEKSMK
190 200 210 220 230 240
THSEDDKDLS KIAVVAVTIF VSAIILAAIG IGIVITVHLW KRYFREYEGE TEERRRLRQE
NGTVHAIA
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P31955-27-unknown | LELNDP... | 27 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P31955-83-unknown | EPQISG... | 83 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27844 | |||
| P31955-100-unknown | VIKPKK... | 100 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P31955-100-unknown | VIKPKK... | 100 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27845 | |||
| P31955-181-unknown | THSEDD... | 181 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27846 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...EEYDNE | 82 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27844 | |||
| ...VRVEQV | 99 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27845 | |||
| ...EKSMKT | 180 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27846 | |||
| ...VHAIA | 248 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ADA17_MOUSE | 82 | YDNE.|.EPQI | inferred from experiment | unknown | MEROPS | Lee DC | Hinkle CL et al.:Selective roles for tumor necro... (M12.217) | 15066986, |
| ADA17_MOUSE | 99 | VEQV.|.VIKP | inferred from experiment | unknown | MEROPS | Lee DC | Hinkle CL et al.:Selective roles for tumor necro... (M12.217) | 15066986, |
| ADA17_MOUSE | 180 | SMKT.|.THSE | inferred from experiment | unknown | MEROPS | Lee DC | Hinkle CL et al.:Selective roles for tumor necro... (M12.217) | 15066986, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|