P32329: Aspartic proteinase 3
| Protein names | - Aspartic proteinase 3 - 3.4.23.41 - Proprotein convertase - Yapsin-1 - Aspartic proteinase 3 subunit alpha - Aspartic proteinase 3 subunit beta |
|---|---|
| Gene names | YPS1 |
| Organism | Saccharomyces cerevisiae |
| Protease Family | A01.030 |
| Protease ID | A01.030 |
| Chromosome location | |
| UniProt ID | P32329 |
5
N-termini
4
C-termini
2
Cleavages
1
Substrates
Sequence
10 20 30 40 50 60
MKLKTVRSAV LSSLFASQVL GKIIPAANKR DDDSNSKFVK LPFHKLYGDS LENVGSDKKP
70 80 90 100 110 120
EVRLLKRADG YEEIIITNQQ SFYSVDLEVG TPPQNVTVLV DTGSSDLWIM GSDNPYCSSN
130 140 150 160 170 180
SMGSSRRRVI DKRDDSSSGG SLINDINPFG WLTGTGSAIG PTATGLGGGS GTATQSVPAS
190 200 210 220 230 240
EATMDCQQYG TFSTSGSSTF RSNNTYFSIS YGDGTFASGT FGTDVLDLSD LNVTGLSFAV
250 260 270 280 290 300
ANETNSTMGV LGIGLPELEV TYSGSTASHS GKAYKYDNFP IVLKNSGAIK SNTYSLYLND
310 320 330 340 350 360
SDAMHGTILF GAVDHSKYTG TLYTIPIVNT LSASGFSSPI QFDVTINGIG ISDSGSSNKT
370 380 390 400 410 420
LTTTKIPALL DSGTTLTYLP QTVVSMIATE LGAQYSSRIG YYVLDCPSDD SMEIVFDFGG
430 440 450 460 470 480
FHINAPLSSF ILSTGTTCLL GIIPTSDDTG TILGDSFLTN AYVVYDLENL EISMAQARYN
490 500 510 520 530 540
TTSENIEIIT SSVPSAVKAP GYTNTWSTSA SIVTGGNIFT VNSSQTASFS GNLTTSTASA
550 560
TSTSSKRNVG DHIVPSLPLT LISLLFAFI
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
5 N-termini - 4 C-termini - 2 Cleavages - 1 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P32329-22-unknown | KIIPAA... | 22 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P32329-31-unknown | DDDSNS... | 31 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32029 | |||
| P32329-67-unknown | RADGYE... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32675 | |||
| P32329-68-unknown | ADGYEE... | 68 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P32329-145-unknown | DINPFG... | 145 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...AANKRD | 30 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32029 | |||
| ...VRLLKR | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32675 | |||
| ...SSRRRV | 128 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...SSKRNV | 548 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| KEX2_YEAST | 30 | NKRD.|.DDDS | inferred from experiment | unknown | MEROPS | Hube B | Bader O et al.:Processing of predicted substra... (S08.070) | 18625069, |
| YPS1_YEAST | 66 | LLKR.|.RADG | inferred from experiment | unknown | MEROPS | Merops YPS1_YEAST -> YPS1_YEAST @66 |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| YPS1_YEAST | 66 | LLKR.|.RADG | inferred from experiment | unknown | MEROPS | Merops YPS1_YEAST -> YPS1_YEAST @66 |