TopFIND 4.0

P32455: Guanylate-binding protein 1

General Information

Protein names
- Guanylate-binding protein 1
- 3.6.5.- {ECO:0000269|PubMed:10676968, ECO:0000269|PubMed:16511497}
- GTP-binding protein 1
- GBP-1
- HuGBP-1
- Guanine nucleotide-binding protein 1
- Interferon-induced guanylate-binding protein 1
Gene names GBP1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P32455

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASEIHMTGP MCLIENTNGR LMANPEALKI LSAITQPMVV VAIVGLYRTG KSYLMNKLAG 
        70         80         90        100        110        120 
KKKGFSLGST VQSHTKGIWM WCVPHPKKPG HILVLLDTEG LGDVEKGDNQ NDSWIFALAV 
       130        140        150        160        170        180 
LLSSTFVYNS IGTINQQAMD QLYYVTELTH RIRSKSSPDE NENEVEDSAD FVSFFPDFVW 
       190        200        210        220        230        240 
TLRDFSLDLE ADGQPLTPDE YLTYSLKLKK GTSQKDETFN LPRLCIRKFF PKKKCFVFDR 
       250        260        270        280        290        300 
PVHRRKLAQL EKLQDEELDP EFVQQVADFC SYIFSNSKTK TLSGGIQVNG PRLESLVLTY 
       310        320        330        340        350        360 
VNAISSGDLP CMENAVLALA QIENSAAVQK AIAHYEQQMG QKVQLPTETL QELLDLHRDS 
       370        380        390        400        410        420 
EREAIEVFIR SSFKDVDHLF QKELAAQLEK KRDDFCKQNQ EASSDRCSAL LQVIFSPLEE 
       430        440        450        460        470        480 
EVKAGIYSKP GGYRLFVQKL QDLKKKYYEE PRKGIQAEEI LQTYLKSKES MTDAILQTDQ 
       490        500        510        520        530        540 
TLTEKEKEIE VERVKAESAQ ASAKMLQEMQ RKNEQMMEQK ERSYQEHLKQ LTEKMENDRV 
       550        560        570        580        590    
QLLKEQERTL ALKLQEQEQL LKEGFQKESR IMKNEIQDLQ TKMRRRKACT IS

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P32455-1-unknown MASEIH... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P32455-193- GQPLTP... 193 Subtiligase Based Positive Selection Wells apoptotic_MM1s_bort 23264352

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RRKACT 589 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)