P32780: General transcription factor IIH subunit 1

General Information

Protein names	- General transcription factor IIH subunit 1 - Basic transcription factor 2 62 kDa subunit - BTF2 p62 - General transcription factor IIH polypeptide 1 - TFIIH basal transcription factor complex p62 subunit
Gene names	GTF2H1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P32780

6 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATSSEEVLL IVKKVRQKKQ DGALYLMAER IAWAPEGKDR FTISHMYADI KCQKISPEGK
        70         80         90        100        110        120
AKIQLQLVLH AGDTTNFHFS NESTAVKERD AVKDLLQQLL PKFKRKANKE LEEKNRMLQE
       130        140        150        160        170        180
DPVLFQLYKD LVVSQVISAE EFWANRLNVN ATDSSSTSNH KQDVGISAAF LADVRPQTDG
       190        200        210        220        230        240
CNGLRYNLTS DIIESIFRTY PAVKMKYAEN VPHNMTEKEF WTRFFQSHYF HRDRLNTGSK
       250        260        270        280        290        300
DLFAECAKID EKGLKTMVSL GVKNPLLDLT ALEDKPLDEG YGISSVPSAS NSKSIKENSN
       310        320        330        340        350        360
AAIIKRFNHH SAMVLAAGLR KQEAQNEQTS EPSNMDGNSG DADCFQPAVK RAKLQESIEY
       370        380        390        400        410        420
EDLGKNNSVK TIALNLKKSD RYYHGPTPIQ SLQYATSQDI INSFQSIRQE MEAYTPKLTQ
       430        440        450        460        470        480
VLSSSAASST ITALSPGGAL MQGGTQQAIN QMVPNDIQSE LKHLYVAVGE LLRHFWSCFP
       490        500        510        520        530        540
VNTPFLEEKV VKMKSNLERF QVTKLCPFQE KIRRQYLSTN LVSHIEEMLQ TAYNKLHTWQ

SRRLMKKT

Isoforms

- Isoform 2 of General transcription factor IIH subunit 1

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P32780-1-unknown	MATSSE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P32780-2-acetylation	ATSSEE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P32780-117-unknown	MLQEDP...	117		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000435375
P32780-205-unknown	MKYAEN...	205		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000436575
P32780-313-unknown	MVLAAG...	313		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000433133
P32780-411-unknown	MEAYTP...	411		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000439774

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...AVKDLL	95	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000431481
	...LMKKT	548	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)