TopFIND 4.0

P33260: Cytochrome P450 2C18

General Information

Protein names
- Cytochrome P450 2C18
- 1.14.14.1
- CYPIIC18
- Cytochrome P450-6b/29c
Gene names CYP2C18
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P33260

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDPAVALVLC LSCLFLLSLW RQSSGRGRLP SGPTPLPIIG NILQLDVKDM SKSLTNFSKV 
        70         80         90        100        110        120 
YGPVFTVYFG LKPIVVLHGY EAVKEALIDH GEEFSGRGSF PVAEKVNKGL GILFSNGKRW 
       130        140        150        160        170        180 
KEIRRFCLMT LRNFGMGKRS IEDRVQEEAR CLVEELRKTN ASPCDPTFIL GCAPCNVICS 
       190        200        210        220        230        240 
VIFHDRFDYK DQRFLNLMEK FNENLRILSS PWIQVCNNFP ALIDYLPGSH NKIAENFAYI 
       250        260        270        280        290        300 
KSYVLERIKE HQESLDMNSA RDFIDCFLIK MEQEKHNQQS EFTVESLIAT VTDMFGAGTE 
       310        320        330        340        350        360 
TTSTTLRYGL LLLLKYPEVT AKVQEEIECV VGRNRSPCMQ DRSHMPYTDA VVHEIQRYID 
       370        380        390        400        410        420 
LLPTNLPHAV TCDVKFKNYL IPKGTTIITS LTSVLHNDKE FPNPEMFDPG HFLDKSGNFK 
       430        440        450        460        470        480 
KSDYFMPFSA GKRMCMGEGL ARMELFLFLT TILQNFNLKS QVDPKDIDIT PIANAFGRVP 
       490    
PLYQLCFIPV 

Isoforms

- Isoform 2 of Cytochrome P450 2C18

Sequence View

        10         20         30         40         50         60 
MDPAVALVLC LSCLFLLSLW RQSSGRGRLP SGPTPLPIIG NILQLDVKDM SKSLTNFSKV 
        70         80         90        100        110        120 
YGPVFTVYFG LKPIVVLHGY EAVKEALIDH GEEFSGRGSF PVAEKVNKGL GILFSNGKRW 
       130        140        150        160        170        180 
KEIRRFCLMT LRNFGMGKRS IEDRVQEEAR CLVEELRKTN ASPCDPTFIL GCAPCNVICS 
       190        200        210        220        230        240 
VIFHDRFDYK DQRFLNLMEK FNENLRILSS PWIQVCNNFP ALIDYLPGSH NKIAENFAYI 
       250        260        270        280        290        300 
KSYVLERIKE HQESLDMNSA RDFIDCFLIK MEQEKHNQQS EFTVESLIAT VTDMFGAGTE 
       310        320        330        340        350        360 
TTSTTLRYGL LLLLKYPEVT AKVQEEIECV VGRNRSPCMQ DRSHMPYTDA VVHEIQRYID 
       370        380        390        400        410        420 
LLPTNLPHAV TCDVKFKNYL IPKGTTIITS LTSVLHNDKE FPNPEMFDPG HFLDKSGNFK 
       430        440        450        460        470        480 
KSDYFMPFSA GKRMCMGEGL ARMELFLFLT TILQNFNLKS QVDPKDIDIT PIANAFGRVP 
       490    
PLYQLCFIPV 



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P33260-1-unknown MDPAVA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P33260-1-unknown MDPAVA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71517

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CFIPV 490 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...CFIPV 490 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt67135

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)