TopFIND 4.0

P33261: Cytochrome P450 2C19

General Information

Protein names
- Cytochrome P450 2C19
- 1.14.14.- {ECO:0000269|PubMed:18577768}
- (R)-limonene 6-monooxygenase
- 1.14.14.53 {ECO:0000269|PubMed:11950794}
- (S)-limonene 6-monooxygenase
- 1.14.14.51 {ECO:0000269|PubMed:11950794}
- (S)-limonene 7-monooxygenase
- 1.14.14.52 {ECO:0000269|PubMed:11950794}
- CYPIIC17
- CYPIIC19
- Cytochrome P450-11A
- Cytochrome P450-254C
- Fenbendazole monooxygenase (4'-hydroxylating) {ECO:0000305}
- 1.14.14.75 {ECO:0000269|PubMed:23959307}
- Mephenytoin 4-hydroxylase
Gene names CYP2C19
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P33261

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDPFVVLVLC LSCLLLLSIW RQSSGRGKLP PGPTPLPVIG NILQIDIKDV SKSLTNLSKI 
        70         80         90        100        110        120 
YGPVFTLYFG LERMVVLHGY EVVKEALIDL GEEFSGRGHF PLAERANRGF GIVFSNGKRW 
       130        140        150        160        170        180 
KEIRRFSLMT LRNFGMGKRS IEDRVQEEAR CLVEELRKTK ASPCDPTFIL GCAPCNVICS 
       190        200        210        220        230        240 
IIFQKRFDYK DQQFLNLMEK LNENIRIVST PWIQICNNFP TIIDYFPGTH NKLLKNLAFM 
       250        260        270        280        290        300 
ESDILEKVKE HQESMDINNP RDFIDCFLIK MEKEKQNQQS EFTIENLVIT AADLLGAGTE 
       310        320        330        340        350        360 
TTSTTLRYAL LLLLKHPEVT AKVQEEIERV VGRNRSPCMQ DRGHMPYTDA VVHEVQRYID 
       370        380        390        400        410        420 
LIPTSLPHAV TCDVKFRNYL IPKGTTILTS LTSVLHDNKE FPNPEMFDPR HFLDEGGNFK 
       430        440        450        460        470        480 
KSNYFMPFSA GKRICVGEGL ARMELFLFLT FILQNFNLKS LIDPKDLDTT PVVNGFASVP 
       490    
PFYQLCFIPV 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P33261-1-unknown MDPFVV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CFIPV 490 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)