TopFIND 4.0

P34914: Bifunctional epoxide hydrolase 2

General Information

Protein names
- Bifunctional epoxide hydrolase 2
- Cytosolic epoxide hydrolase 2
- CEH
- 3.3.2.10 {ECO:0000250|UniProtKB:P34913}
- Epoxide hydratase
- Soluble epoxide hydrolase
- SEH
- Lipid-phosphate phosphatase
- 3.1.3.76 {ECO:0000250|UniProtKB:P34913}
Gene names Ephx2
Organism Mus musculus
Protease Family
Protease ID S33.973
Chromosome location
UniProt ID P34914

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MALRVAAFDL DGVLALPSIA GAFRRSEEAL ALPRDFLLGA YQTEFPEGPT EQLMKGKITF 
        70         80         90        100        110        120 
SQWVPLMDES YRKSSKACGA NLPENFSISQ IFSQAMAARS INRPMLQAAI ALKKKGFTTC 
       130        140        150        160        170        180 
IVTNNWLDDG DKRDSLAQMM CELSQHFDFL IESCQVGMIK PEPQIYNFLL DTLKAKPNEV 
       190        200        210        220        230        240 
VFLDDFGSNL KPARDMGMVT ILVHNTASAL RELEKVTGTQ FPEAPLPVPC NPNDVSHGYV 
       250        260        270        280        290        300 
TVKPGIRLHF VEMGSGPALC LCHGFPESWF SWRYQIPALA QAGFRVLAID MKGYGDSSSP 
       310        320        330        340        350        360 
PEIEEYAMEL LCKEMVTFLD KLGIPQAVFI GHDWAGVMVW NMALFYPERV RAVASLNTPF 
       370        380        390        400        410        420 
MPPDPDVSPM KVIRSIPVFN YQLYFQEPGV AEAELEKNMS RTFKSFFRAS DETGFIAVHK 
       430        440        450        460        470        480 
ATEIGGILVN TPEDPNLSKI TTEEEIEFYI QQFKKTGFRG PLNWYRNTER NWKWSCKGLG 
       490        500        510        520        530        540 
RKILVPALMV TAEKDIVLRP EMSKNMEKWI PFLKRGHIED CGHWTQIEKP TEVNQILIKW 
       550    
LQTEVQNPSV TSKI

Isoforms

- Isoform 2 of Bifunctional epoxide hydrolase 2

Sequence View

        10         20         30         40         50         60 
MALRVAAFDL DGVLALPSIA GAFRRSEEAL ALPRDFLLGA YQTEFPEGPT EQLMKGKITF 
        70         80         90        100        110        120 
SQWVPLMDES YRKSSKACGA NLPENFSISQ IFSQAMAARS INRPMLQAAI ALKKKGFTTC 
       130        140        150        160        170        180 
IVTNNWLDDG DKRDSLAQMM CELSQHFDFL IESCQVGMIK PEPQIYNFLL DTLKAKPNEV 
       190        200        210        220        230        240 
VFLDDFGSNL KPARDMGMVT ILVHNTASAL RELEKVTGTQ FPEAPLPVPC NPNDVSHGYV 
       250        260        270        280        290        300 
TVKPGIRLHF VEMGSGPALC LCHGFPESWF SWRYQIPALA QAGFRVLAID MKGYGDSSSP 
       310        320        330        340        350        360 
PEIEEYAMEL LCKEMVTFLD KLGIPQAVFI GHDWAGVMVW NMALFYPERV RAVASLNTPF 
       370        380        390        400        410        420 
MPPDPDVSPM KVIRSIPVFN YQLYFQEPGV AEAELEKNMS RTFKSFFRAS DETGFIAVHK 
       430        440        450        460        470        480 
ATEIGGILVN TPEDPNLSKI TTEEEIEFYI QQFKKTGFRG PLNWYRNTER NWKWSCKGLG 
       490        500        510        520        530        540 
RKILVPALMV TAEKDIVLRP EMSKNMEKWI PFLKRGHIED CGHWTQIEKP TEVNQILIKW 
       550    
LQTEVQNPSV TSKI



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P34914-1-unknown MALRVA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VTSKI 554 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VTSKI 554 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73009

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)