P34998: Corticotropin-releasing factor receptor 1

General Information

Protein names	- Corticotropin-releasing factor receptor 1 - CRF-R-1 - CRF-R1 - CRFR-1 - Corticotropin-releasing hormone receptor 1 - CRH-R-1 - CRH-R1
Gene names	CRHR1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P34998

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 - Isoform CRF-R3 of Corticotropin-releasing factor receptor 1 - Isoform CRF-R4 of Corticotropin-releasing factor receptor 1 - Isoform 5 of Corticotropin-releasing factor receptor 1

Sequence View

        10         20         30         40         50         60
MGGHPQLRLV KALLLLGLNP VSASLQDQHC ESLSLASNIS GLQCNASVDL IGTCWPRSPA
        70         80         90        100        110        120
GQLVVRPCPA FFYGVRYNTT NNGYRECLAN GSWAARVNYS ECQEILNEEK KSKVHYHVAV
       130        140        150        160        170        180
IINYLGHCIS LVALLVAFVL FLRLRPGCTH WGDQADGALE VGAPWSGAPF QVRRSIRCLR
       190        200        210        220        230        240
NIIHWNLISA FILRNATWFV VQLTMSPEVH QSNVGWCRLV TAAYNYFHVT NFFWMFGEGC
       250        260        270        280        290        300
YLHTAIVLTY STDRLRKWMF ICIGWGVPFP IIVAWAIGKL YYDNEKCWFG KRPGVYTDYI
       310        320        330        340        350        360
YQGPMILVLL INFIFLFNIV RILMTKLRAS TTSETIQYRK AVKATLVLLP LLGITYMLFF
       370        380        390        400        410        420
VNPGEDEVSR VVFIYFNSFL ESFQGFFVSV FYCFLNSEVR SAIRKRWHRW QDKHSIRARV
       430        440
ARAMSIPTSP TRVSFHSIKQ STAV         10         20         30         40         50         60
MGGHPQLRLV KALLLLGLNP VSASLQDQHC ESLSLASNIS GLQCNASVDL IGTCWPRSPA
        70         80         90        100        110        120
GQLVVRPCPA FFYGVRYNTT NNGYRECLAN GSWAARVNYS ECQEILNEEK KSKVHYHVAV
       130        140        150        160        170        180
IINYLGHCIS LVALLVAFVL FLRLRPGCTH WGDQADGALE VGAPWSGAPF QVRRSIRCLR
       190        200        210        220        230        240
NIIHWNLISA FILRNATWFV VQLTMSPEVH QSNVGWCRLV TAAYNYFHVT NFFWMFGEGC
       250        260        270        280        290        300
YLHTAIVLTY STDRLRKWMF ICIGWGVPFP IIVAWAIGKL YYDNEKCWFG KRPGVYTDYI
       310        320        330        340        350        360
YQGPMILVLL INFIFLFNIV RILMTKLRAS TTSETIQYRK AVKATLVLLP LLGITYMLFF
       370        380        390        400        410        420
VNPGEDEVSR VVFIYFNSFL ESFQGFFVSV FYCFLNSEVR SAIRKRWHRW QDKHSIRARV
       430        440
ARAMSIPTSP TRVSFHSIKQ STAV         10         20         30         40         50         60
MGGHPQLRLV KALLLLGLNP VSASLQDQHC ESLSLASNIS GLQCNASVDL IGTCWPRSPA
        70         80         90        100        110        120
GQLVVRPCPA FFYGVRYNTT NNGYRECLAN GSWAARVNYS ECQEILNEEK KSKVHYHVAV
       130        140        150        160        170        180
IINYLGHCIS LVALLVAFVL FLRLRPGCTH WGDQADGALE VGAPWSGAPF QVRRSIRCLR
       190        200        210        220        230        240
NIIHWNLISA FILRNATWFV VQLTMSPEVH QSNVGWCRLV TAAYNYFHVT NFFWMFGEGC
       250        260        270        280        290        300
YLHTAIVLTY STDRLRKWMF ICIGWGVPFP IIVAWAIGKL YYDNEKCWFG KRPGVYTDYI
       310        320        330        340        350        360
YQGPMILVLL INFIFLFNIV RILMTKLRAS TTSETIQYRK AVKATLVLLP LLGITYMLFF
       370        380        390        400        410        420
VNPGEDEVSR VVFIYFNSFL ESFQGFFVSV FYCFLNSEVR SAIRKRWHRW QDKHSIRARV
       430        440
ARAMSIPTSP TRVSFHSIKQ STAV         10         20         30         40         50         60
MGGHPQLRLV KALLLLGLNP VSASLQDQHC ESLSLASNIS GLQCNASVDL IGTCWPRSPA
        70         80         90        100        110        120
GQLVVRPCPA FFYGVRYNTT NNGYRECLAN GSWAARVNYS ECQEILNEEK KSKVHYHVAV
       130        140        150        160        170        180
IINYLGHCIS LVALLVAFVL FLRLRPGCTH WGDQADGALE VGAPWSGAPF QVRRSIRCLR
       190        200        210        220        230        240
NIIHWNLISA FILRNATWFV VQLTMSPEVH QSNVGWCRLV TAAYNYFHVT NFFWMFGEGC
       250        260        270        280        290        300
YLHTAIVLTY STDRLRKWMF ICIGWGVPFP IIVAWAIGKL YYDNEKCWFG KRPGVYTDYI
       310        320        330        340        350        360
YQGPMILVLL INFIFLFNIV RILMTKLRAS TTSETIQYRK AVKATLVLLP LLGITYMLFF
       370        380        390        400        410        420
VNPGEDEVSR VVFIYFNSFL ESFQGFFVSV FYCFLNSEVR SAIRKRWHRW QDKHSIRARV
       430        440
ARAMSIPTSP TRVSFHSIKQ STAV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P34998-1-unknown	MGGHPQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71721
P34998-1-unknown	MGGHPQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71722
P34998-1-unknown	MGGHPQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71723
P34998-24-unknown	SLQDQH...	24	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P34998-24-unknown	SLQDQH...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113678
P34998-24-unknown	SLQDQH...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113679
P34998-205-unknown	MSPEVH...	205	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71724
P34998-205-unknown	MSPEVH...	205	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt98343
P34998-205-unknown	MSPEVH...	205	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt98342
P34998-205-unknown	MSPEVH...	205	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt98344

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QSTAV	444	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QSTAV	444	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67342
...QSTAV	444	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67340
...QSTAV	444	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67341
...QSTAV	444	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67339

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)