TopFIND 4.0

P35080: Profilin-2

General Information

Protein names
- Profilin-2
- Profilin II
Gene names PFN2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P35080

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGWQSYVDN LMCDGCCQEA AIVGYCDAKY VWAATAGGVF QSITPIEIDM IVGKDREGFF 
        70         80         90        100        110        120 
TNGLTLGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRVL VFVMGKEGVH 
       130        140    
GGGLNKKAYS MAKYLRDSGF 

Isoforms

- Isoform IIb of Profilin-2

Sequence View

        10         20         30         40         50         60 
MAGWQSYVDN LMCDGCCQEA AIVGYCDAKY VWAATAGGVF QSITPIEIDM IVGKDREGFF 
        70         80         90        100        110        120 
TNGLTLGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRVL VFVMGKEGVH 
       130        140    
GGGLNKKAYS MAKYLRDSGF 



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P35080-2-unknown MAGWQS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P35080-1-unknown MAGWQS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt86234
    P35080-2-Acetylation AGWQSY... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P35080-2-Acetylation AGWQSY... 2 acetylation- other CNRS/ISV Large_scale_NTA_Human
    P35080-2-Acetylation AGWQSY... 2 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt110140

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RDSGF 140 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)