P35247: Pulmonary surfactant-associated protein D

General Information

Protein names	- Pulmonary surfactant-associated protein D - PSP-D - SP-D - Collectin-7 - Lung surfactant protein D
Gene names	SFTPD
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P35247

6 N-termini

7 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLLFLLSALV LLTQPLGYLE AEMKTYSHRT MPSACTLVMC SSVESGLPGR DGRDGREGPR
        70         80         90        100        110        120
GEKGDPGLPG AAGQAGMPGQ AGPVGPKGDN GSVGEPGPKG DTGPSGPPGP PGVPGPAGRE
       130        140        150        160        170        180
GPLGKQGNIG PQGKPGPKGE AGPKGEVGAP GMQGSAGARG LAGPKGERGV PGERGVPGNT
       190        200        210        220        230        240
GAAGSAGAMG PQGSPGARGP PGLKGDKGIP GDKGAKGESG LPDVASLRQQ VEALQGQVQH
       250        260        270        280        290        300
LQAAFSQYKK VELFPNGQSV GEKIFKTAGF VKPFTEAQLL CTQAGGQLAS PRSAAENAAL
       310        320        330        340        350        360
QQLVVAKNEA AFLSMTDSKT EGKFTYPTGE SLVYSNWAPG EPNDDGGSED CVEIFTNGKW
       370
NDRACGEKRL VVCEF

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 7 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P35247-21-unknown	AEMKTY...	21	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P35247-21-unknown	AEMKTY...	21	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P35247-132-unknown	QGKPGP...	132	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9431
P35247-252-unknown	ELFPNG...	252	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9432
P35247-278-unknown	QLLCTQ...	278	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9433
P35247-312-unknown	FLSMTD...	312	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9434
P35247-334-unknown	YSNWAP...	334	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9435

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GNIGPQ	131	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9431
...PGLKGD	205	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394325
...QYKKVE	251	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9432
...PFTEAQ	277	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9433
...KNEAAF	311	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9434
...GESLVY	333	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9435
...VVCEF	375	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
ELNE_HUMAN	131	IGPQ.\|.QGKP	inferred from experiment	unknown	MEROPS	von Bredow Ch	Griese M et al.:Limited proteolysis of surfacta... (S01.131)	12853121,
ELNE_HUMAN	251	KKVE.\|.ELFP	inferred from experiment	unknown	MEROPS	von Bredow Ch	Griese M et al.:Limited proteolysis of surfacta... (S01.131)	12853121,
ELNE_HUMAN	277	TEAQ.\|.QLLC	inferred from experiment	unknown	MEROPS	von Bredow Ch	Griese M et al.:Limited proteolysis of surfacta... (S01.131)	12853121,
ELNE_HUMAN	311	EAAF.\|.FLSM	inferred from experiment	unknown	MEROPS	von Bredow Ch	Griese M et al.:Limited proteolysis of surfacta... (S01.131)	12853121,
ELNE_HUMAN	333	SLVY.\|.YSNW	inferred from experiment	unknown	MEROPS	von Bredow Ch	Griese M et al.:Limited proteolysis of surfacta... (S01.131)	12853121,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)