P35249: Replication factor C subunit 4

General Information

Protein names	- Replication factor C subunit 4 - Activator 1 37 kDa subunit - A1 37 kDa subunit - Activator 1 subunit 4 - Replication factor C 37 kDa subunit - RF-C 37 kDa subunit - RFC37
Gene names	RFC4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P35249

3 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MQAFLKGTSI STKPPLTKDR GVAASAGSSG ENKKAKPVPW VEKYRPKCVD EVAFQEEVVA
        70         80         90        100        110        120
VLKKSLEGAD LPNLLFYGPP GTGKTSTILA AARELFGPEL FRLRVLELNA SDERGIQVVR
       130        140        150        160        170        180
EKVKNFAQLT VSGSRSDGKP CPPFKIVILD EADSMTSAAQ AALRRTMEKE SKTTRFCLIC
       190        200        210        220        230        240
NYVSRIIEPL TSRCSKFRFK PLSDKIQQQR LLDIAKKENV KISDEGIAYL VKVSEGDLRK
       250        260        270        280        290        300
AITFLQSATR LTGGKEITEK VITDIAGVIP AEKIDGVFAA CQSGSFDKLE AVVKDLIDEG
       310        320        330        340        350        360
HAATQLVNQL HDVVVENNLS DKQKSIITEK LAEVDKCLAD GADEHLQLIS LCATVMQQLS

QNC

Isoforms

- Isoform 2 of Replication factor C subunit 4

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P35249-1-Acetylation	MQAFLK...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P35249-1-Acetylation	MQAFLK...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P35249-1-Acetylation	MQAFLK...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P35249-154-	SMTSAA...	154			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P35249-226-unknown	GIAYLV...	226		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000401429

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PWVEKY	43	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399314
...AARELF	95	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415099
...VREKVK	123	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000407982
...LRRTME	167	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000413065
...RLLDIA	214	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411300
...LSQNC	363	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)