P35348: Alpha-1A adrenergic receptor

General Information

Protein names	- Alpha-1A adrenergic receptor - Alpha-1A adrenoreceptor - Alpha-1A adrenoceptor - Alpha-1C adrenergic receptor - Alpha-adrenergic receptor 1c
Gene names	ADRA1A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P35348

1 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Alpha-1A adrenergic receptor - Isoform 3 of Alpha-1A adrenergic receptor - Isoform 4 of Alpha-1A adrenergic receptor - Isoform 5 of Alpha-1A adrenergic receptor - Isoform 6 of Alpha-1A adrenergic receptor - Isoform 7 of Alpha-1A adrenergic receptor - Isoform 8 of Alpha-1A adrenergic receptor - Isoform 9 of Alpha-1A adrenergic receptor

Sequence View

        10         20         30         40         50         60
MVFLSGNASD SSNCTQPPAP VNISKAILLG VILGGLILFG VLGNILVILS VACHRHLHSV
        70         80         90        100        110        120
THYYIVNLAV ADLLLTSTVL PFSAIFEVLG YWAFGRVFCN IWAAVDVLCC TASIMGLCII
       130        140        150        160        170        180
SIDRYIGVSY PLRYPTIVTQ RRGLMALLCV WALSLVISIG PLFGWRQPAP EDETICQINE
       190        200        210        220        230        240
EPGYVLFSAL GSFYLPLAII LVMYCRVYVV AKRESRGLKS GLKTDKSDSE QVTLRIHRKN
       250        260        270        280        290        300
APAGGSGMAS AKTKTHFSVR LLKFSREKKA AKTLGIVVGC FVLCWLPFFL VMPIGSFFPD
       310        320        330        340        350        360
FKPSETVFKI VFWLGYLNSC INPIIYPCSS QEFKKAFQNV LRIQCLCRKQ SSKHALGYTL
       370        380        390        400        410        420
HPPSQAVEGQ HKDMVRIPVG SRETFYRISK TDGVCEWKFF SSMPRGSARI TVSKDQSSCT
       430        440        450        460
TARVRSKSFL QVCCCVGPST PSLDKNHQVP TIKVHTISLS ENGEEV         10         20         30         40         50         60
MVFLSGNASD SSNCTQPPAP VNISKAILLG VILGGLILFG VLGNILVILS VACHRHLHSV
        70         80         90        100        110        120
THYYIVNLAV ADLLLTSTVL PFSAIFEVLG YWAFGRVFCN IWAAVDVLCC TASIMGLCII
       130        140        150        160        170        180
SIDRYIGVSY PLRYPTIVTQ RRGLMALLCV WALSLVISIG PLFGWRQPAP EDETICQINE
       190        200        210        220        230        240
EPGYVLFSAL GSFYLPLAII LVMYCRVYVV AKRESRGLKS GLKTDKSDSE QVTLRIHRKN
       250        260        270        280        290        300
APAGGSGMAS AKTKTHFSVR LLKFSREKKA AKTLGIVVGC FVLCWLPFFL VMPIGSFFPD
       310        320        330        340        350        360
FKPSETVFKI VFWLGYLNSC INPIIYPCSS QEFKKAFQNV LRIQCLCRKQ SSKHALGYTL
       370        380        390        400        410        420
HPPSQAVEGQ HKDMVRIPVG SRETFYRISK TDGVCEWKFF SSMPRGSARI TVSKDQSSCT
       430        440        450        460
TARVRSKSFL QVCCCVGPST PSLDKNHQVP TIKVHTISLS ENGEEV         10         20         30         40         50         60
MVFLSGNASD SSNCTQPPAP VNISKAILLG VILGGLILFG VLGNILVILS VACHRHLHSV
        70         80         90        100        110        120
THYYIVNLAV ADLLLTSTVL PFSAIFEVLG YWAFGRVFCN IWAAVDVLCC TASIMGLCII
       130        140        150        160        170        180
SIDRYIGVSY PLRYPTIVTQ RRGLMALLCV WALSLVISIG PLFGWRQPAP EDETICQINE
       190        200        210        220        230        240
EPGYVLFSAL GSFYLPLAII LVMYCRVYVV AKRESRGLKS GLKTDKSDSE QVTLRIHRKN
       250        260        270        280        290        300
APAGGSGMAS AKTKTHFSVR LLKFSREKKA AKTLGIVVGC FVLCWLPFFL VMPIGSFFPD
       310        320        330        340        350        360
FKPSETVFKI VFWLGYLNSC INPIIYPCSS QEFKKAFQNV LRIQCLCRKQ SSKHALGYTL
       370        380        390        400        410        420
HPPSQAVEGQ HKDMVRIPVG SRETFYRISK TDGVCEWKFF SSMPRGSARI TVSKDQSSCT
       430        440        450        460
TARVRSKSFL QVCCCVGPST PSLDKNHQVP TIKVHTISLS ENGEEV         10         20         30         40         50         60
MVFLSGNASD SSNCTQPPAP VNISKAILLG VILGGLILFG VLGNILVILS VACHRHLHSV
        70         80         90        100        110        120
THYYIVNLAV ADLLLTSTVL PFSAIFEVLG YWAFGRVFCN IWAAVDVLCC TASIMGLCII
       130        140        150        160        170        180
SIDRYIGVSY PLRYPTIVTQ RRGLMALLCV WALSLVISIG PLFGWRQPAP EDETICQINE
       190        200        210        220        230        240
EPGYVLFSAL GSFYLPLAII LVMYCRVYVV AKRESRGLKS GLKTDKSDSE QVTLRIHRKN
       250        260        270        280        290        300
APAGGSGMAS AKTKTHFSVR LLKFSREKKA AKTLGIVVGC FVLCWLPFFL VMPIGSFFPD
       310        320        330        340        350        360
FKPSETVFKI VFWLGYLNSC INPIIYPCSS QEFKKAFQNV LRIQCLCRKQ SSKHALGYTL
       370        380        390        400        410        420
HPPSQAVEGQ HKDMVRIPVG SRETFYRISK TDGVCEWKFF SSMPRGSARI TVSKDQSSCT
       430        440        450        460
TARVRSKSFL QVCCCVGPST PSLDKNHQVP TIKVHTISLS ENGEEV         10         20         30         40         50         60
MVFLSGNASD SSNCTQPPAP VNISKAILLG VILGGLILFG VLGNILVILS VACHRHLHSV
        70         80         90        100        110        120
THYYIVNLAV ADLLLTSTVL PFSAIFEVLG YWAFGRVFCN IWAAVDVLCC TASIMGLCII
       130        140        150        160        170        180
SIDRYIGVSY PLRYPTIVTQ RRGLMALLCV WALSLVISIG PLFGWRQPAP EDETICQINE
       190        200        210        220        230        240
EPGYVLFSAL GSFYLPLAII LVMYCRVYVV AKRESRGLKS GLKTDKSDSE QVTLRIHRKN
       250        260        270        280        290        300
APAGGSGMAS AKTKTHFSVR LLKFSREKKA AKTLGIVVGC FVLCWLPFFL VMPIGSFFPD
       310        320        330        340        350        360
FKPSETVFKI VFWLGYLNSC INPIIYPCSS QEFKKAFQNV LRIQCLCRKQ SSKHALGYTL
       370        380        390        400        410        420
HPPSQAVEGQ HKDMVRIPVG SRETFYRISK TDGVCEWKFF SSMPRGSARI TVSKDQSSCT
       430        440        450        460
TARVRSKSFL QVCCCVGPST PSLDKNHQVP TIKVHTISLS ENGEEV         10         20         30         40         50         60
MVFLSGNASD SSNCTQPPAP VNISKAILLG VILGGLILFG VLGNILVILS VACHRHLHSV
        70         80         90        100        110        120
THYYIVNLAV ADLLLTSTVL PFSAIFEVLG YWAFGRVFCN IWAAVDVLCC TASIMGLCII
       130        140        150        160        170        180
SIDRYIGVSY PLRYPTIVTQ RRGLMALLCV WALSLVISIG PLFGWRQPAP EDETICQINE
       190        200        210        220        230        240
EPGYVLFSAL GSFYLPLAII LVMYCRVYVV AKRESRGLKS GLKTDKSDSE QVTLRIHRKN
       250        260        270        280        290        300
APAGGSGMAS AKTKTHFSVR LLKFSREKKA AKTLGIVVGC FVLCWLPFFL VMPIGSFFPD
       310        320        330        340        350        360
FKPSETVFKI VFWLGYLNSC INPIIYPCSS QEFKKAFQNV LRIQCLCRKQ SSKHALGYTL
       370        380        390        400        410        420
HPPSQAVEGQ HKDMVRIPVG SRETFYRISK TDGVCEWKFF SSMPRGSARI TVSKDQSSCT
       430        440        450        460
TARVRSKSFL QVCCCVGPST PSLDKNHQVP TIKVHTISLS ENGEEV         10         20         30         40         50         60
MVFLSGNASD SSNCTQPPAP VNISKAILLG VILGGLILFG VLGNILVILS VACHRHLHSV
        70         80         90        100        110        120
THYYIVNLAV ADLLLTSTVL PFSAIFEVLG YWAFGRVFCN IWAAVDVLCC TASIMGLCII
       130        140        150        160        170        180
SIDRYIGVSY PLRYPTIVTQ RRGLMALLCV WALSLVISIG PLFGWRQPAP EDETICQINE
       190        200        210        220        230        240
EPGYVLFSAL GSFYLPLAII LVMYCRVYVV AKRESRGLKS GLKTDKSDSE QVTLRIHRKN
       250        260        270        280        290        300
APAGGSGMAS AKTKTHFSVR LLKFSREKKA AKTLGIVVGC FVLCWLPFFL VMPIGSFFPD
       310        320        330        340        350        360
FKPSETVFKI VFWLGYLNSC INPIIYPCSS QEFKKAFQNV LRIQCLCRKQ SSKHALGYTL
       370        380        390        400        410        420
HPPSQAVEGQ HKDMVRIPVG SRETFYRISK TDGVCEWKFF SSMPRGSARI TVSKDQSSCT
       430        440        450        460
TARVRSKSFL QVCCCVGPST PSLDKNHQVP TIKVHTISLS ENGEEV         10         20         30         40         50         60
MVFLSGNASD SSNCTQPPAP VNISKAILLG VILGGLILFG VLGNILVILS VACHRHLHSV
        70         80         90        100        110        120
THYYIVNLAV ADLLLTSTVL PFSAIFEVLG YWAFGRVFCN IWAAVDVLCC TASIMGLCII
       130        140        150        160        170        180
SIDRYIGVSY PLRYPTIVTQ RRGLMALLCV WALSLVISIG PLFGWRQPAP EDETICQINE
       190        200        210        220        230        240
EPGYVLFSAL GSFYLPLAII LVMYCRVYVV AKRESRGLKS GLKTDKSDSE QVTLRIHRKN
       250        260        270        280        290        300
APAGGSGMAS AKTKTHFSVR LLKFSREKKA AKTLGIVVGC FVLCWLPFFL VMPIGSFFPD
       310        320        330        340        350        360
FKPSETVFKI VFWLGYLNSC INPIIYPCSS QEFKKAFQNV LRIQCLCRKQ SSKHALGYTL
       370        380        390        400        410        420
HPPSQAVEGQ HKDMVRIPVG SRETFYRISK TDGVCEWKFF SSMPRGSARI TVSKDQSSCT
       430        440        450        460
TARVRSKSFL QVCCCVGPST PSLDKNHQVP TIKVHTISLS ENGEEV

Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P35348-1-unknown	MVFLSG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P35348-1-unknown	MVFLSG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66273
P35348-1-unknown	MVFLSG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66274
P35348-1-unknown	MVFLSG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66275
P35348-1-unknown	MVFLSG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66276
P35348-1-unknown	MVFLSG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66277
P35348-1-unknown	MVFLSG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66278
P35348-1-unknown	MVFLSG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66279
P35348-1-unknown	MVFLSG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66280

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...NGEEV	466	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

P35348: Alpha-1A adrenergic receptor

General Information

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates