TopFIND 4.0

P35790: Choline kinase alpha

General Information

Protein names
- Choline kinase alpha
- CK
- 2.7.1.32 {ECO:0000269|PubMed:19915674}
- CHETK-alpha
- Ethanolamine kinase
- EK
- 2.7.1.82 {ECO:0000269|PubMed:19915674}
Gene names CHKA
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P35790

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKTKFCTGGE AEPSPLGLLL SCGSGSAAPA PGVGQQRDAA SDLESKQLGG QQPPLALPPP 
        70         80         90        100        110        120 
PPLPLPLPLP QPPPPQPPAD EQPEPRTRRR AYLWCKEFLP GAWRGLREDE FHISVIRGGL 
       130        140        150        160        170        180 
SNMLFQCSLP DTTATLGDEP RKVLLRLYGA ILQMRSCNKE GSEQAQKENE FQGAEAMVLE 
       190        200        210        220        230        240 
SVMFAILAER SLGPKLYGIF PQGRLEQFIP SRRLDTEELS LPDISAEIAE KMATFHGMKM 
       250        260        270        280        290        300 
PFNKEPKWLF GTMEKYLKEV LRIKFTEESR IKKLHKLLSY NLPLELENLR SLLESTPSPV 
       310        320        330        340        350        360 
VFCHNDCQEG NILLLEGREN SEKQKLMLID FEYSSYNYRG FDIGNHFCEW MYDYSYEKYP 
       370        380        390        400        410        420 
FFRANIRKYP TKKQQLHFIS SYLPAFQNDF ENLSTEEKSI IKEEMLLEVN RFALASHFLW 
       430        440        450    
GLWSIVQAKI SSIEFGYMDY AQARFDAYFH QKRKLGV

Isoforms

- Isoform 2 of Choline kinase alpha

Sequence View

        10         20         30         40         50         60 
MKTKFCTGGE AEPSPLGLLL SCGSGSAAPA PGVGQQRDAA SDLESKQLGG QQPPLALPPP 
        70         80         90        100        110        120 
PPLPLPLPLP QPPPPQPPAD EQPEPRTRRR AYLWCKEFLP GAWRGLREDE FHISVIRGGL 
       130        140        150        160        170        180 
SNMLFQCSLP DTTATLGDEP RKVLLRLYGA ILQMRSCNKE GSEQAQKENE FQGAEAMVLE 
       190        200        210        220        230        240 
SVMFAILAER SLGPKLYGIF PQGRLEQFIP SRRLDTEELS LPDISAEIAE KMATFHGMKM 
       250        260        270        280        290        300 
PFNKEPKWLF GTMEKYLKEV LRIKFTEESR IKKLHKLLSY NLPLELENLR SLLESTPSPV 
       310        320        330        340        350        360 
VFCHNDCQEG NILLLEGREN SEKQKLMLID FEYSSYNYRG FDIGNHFCEW MYDYSYEKYP 
       370        380        390        400        410        420 
FFRANIRKYP TKKQQLHFIS SYLPAFQNDF ENLSTEEKSI IKEEMLLEVN RFALASHFLW 
       430        440        450    
GLWSIVQAKI SSIEFGYMDY AQARFDAYFH QKRKLGV



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P35790-1-unknown MKTKFC... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P35790-1-unknown MKTKFC... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70573

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RKLGV 457 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RKLGV 457 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt66191

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)