P36269: Glutathione hydrolase 5 proenzyme

General Information

Protein names	- Glutathione hydrolase 5 proenzyme - 3.4.19.13 - Gamma-glutamyl transpeptidase-related enzyme - GGT-rel - Gamma-glutamyltransferase 5 - GGT 5 - 2.3.2.2 - Gamma-glutamyltransferase-like activity 1 - Gamma-glutamyltranspeptidase 5 - Leukotriene-C4 hydrolase - 3.4.19.14 - Glutathione hydrolase 5 heavy chain - Glutathione hydrolase 5 light chain
Gene names	GGT5
Organism	Homo sapiens
Protease Family
Protease ID	T03.002
Chromosome location
UniProt ID	P36269

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Gamma-glutamyltransferase 5 - Isoform 3 of Gamma-glutamyltransferase 5 - Isoform 2 of Glutathione hydrolase 5 proenzyme - Isoform 3 of Glutathione hydrolase 5 proenzyme

Sequence View

        10         20         30         40         50         60
MARGYGATVS LVLLGLGLAL AVIVLAVVLS RHQAPCGPQA FAHAAVAADS KVCSDIGRAI
        70         80         90        100        110        120
LQQQGSPVDA TIAALVCTSV VNPQSMGLGG GVIFTIYNVT TGKVEVINAR ETVPASHAPS
       130        140        150        160        170        180
LLDQCAQALP LGTGAQWIGV PGELRGYAEA HRRHGRLPWA QLFQPTIALL RGGHVVAPVL
       190        200        210        220        230        240
SRFLHNSILR PSLQASTLRQ LFFNGTEPLR PQDPLPWPAL ATTLETVATE GVEVFYTGRL
       250        260        270        280        290        300
GQMLVEDIAK EGSQLTLQDL AKFQPEVVDA LEVPLGDYTL YSPPPPAGGA ILSFILNVLR
       310        320        330        340        350        360
GFNFSTESMA RPEGRVNVYH HLVETLKFAK GQRWRLGDPR SHPKLQNASR DLLGETLAQL
       370        380        390        400        410        420
IRQQIDGRGD HQLSHYSLAE AWGHGTGTSH VSVLGEDGSA VAATSTINTP FGAMVYSPRT
       430        440        450        460        470        480
GIILNNELLD LCERCPRGSG TTPSPVSGDR VGGAPGRCWP PVPGERSPSS MVPSILINKA
       490        500        510        520        530        540
QGSKLVIGGA GGELIISAVA QAIMSKLWLG FDLRAAIAAP ILHVNSKGCV EYEPNFSQEV
       550        560        570        580
QRGLQDRGQN QTQRPFFLNV VQAVSQEGAC VYAVSDLRKS GEAAGY         10         20         30         40         50         60
MARGYGATVS LVLLGLGLAL AVIVLAVVLS RHQAPCGPQA FAHAAVAADS KVCSDIGRAI
        70         80         90        100        110        120
LQQQGSPVDA TIAALVCTSV VNPQSMGLGG GVIFTIYNVT TGKVEVINAR ETVPASHAPS
       130        140        150        160        170        180
LLDQCAQALP LGTGAQWIGV PGELRGYAEA HRRHGRLPWA QLFQPTIALL RGGHVVAPVL
       190        200        210        220        230        240
SRFLHNSILR PSLQASTLRQ LFFNGTEPLR PQDPLPWPAL ATTLETVATE GVEVFYTGRL
       250        260        270        280        290        300
GQMLVEDIAK EGSQLTLQDL AKFQPEVVDA LEVPLGDYTL YSPPPPAGGA ILSFILNVLR
       310        320        330        340        350        360
GFNFSTESMA RPEGRVNVYH HLVETLKFAK GQRWRLGDPR SHPKLQNASR DLLGETLAQL
       370        380        390        400        410        420
IRQQIDGRGD HQLSHYSLAE AWGHGTGTSH VSVLGEDGSA VAATSTINTP FGAMVYSPRT
       430        440        450        460        470        480
GIILNNELLD LCERCPRGSG TTPSPVSGDR VGGAPGRCWP PVPGERSPSS MVPSILINKA
       490        500        510        520        530        540
QGSKLVIGGA GGELIISAVA QAIMSKLWLG FDLRAAIAAP ILHVNSKGCV EYEPNFSQEV
       550        560        570        580
QRGLQDRGQN QTQRPFFLNV VQAVSQEGAC VYAVSDLRKS GEAAGY         10         20         30         40         50         60
MARGYGATVS LVLLGLGLAL AVIVLAVVLS RHQAPCGPQA FAHAAVAADS KVCSDIGRAI
        70         80         90        100        110        120
LQQQGSPVDA TIAALVCTSV VNPQSMGLGG GVIFTIYNVT TGKVEVINAR ETVPASHAPS
       130        140        150        160        170        180
LLDQCAQALP LGTGAQWIGV PGELRGYAEA HRRHGRLPWA QLFQPTIALL RGGHVVAPVL
       190        200        210        220        230        240
SRFLHNSILR PSLQASTLRQ LFFNGTEPLR PQDPLPWPAL ATTLETVATE GVEVFYTGRL
       250        260        270        280        290        300
GQMLVEDIAK EGSQLTLQDL AKFQPEVVDA LEVPLGDYTL YSPPPPAGGA ILSFILNVLR
       310        320        330        340        350        360
GFNFSTESMA RPEGRVNVYH HLVETLKFAK GQRWRLGDPR SHPKLQNASR DLLGETLAQL
       370        380        390        400        410        420
IRQQIDGRGD HQLSHYSLAE AWGHGTGTSH VSVLGEDGSA VAATSTINTP FGAMVYSPRT
       430        440        450        460        470        480
GIILNNELLD LCERCPRGSG TTPSPVSGDR VGGAPGRCWP PVPGERSPSS MVPSILINKA
       490        500        510        520        530        540
QGSKLVIGGA GGELIISAVA QAIMSKLWLG FDLRAAIAAP ILHVNSKGCV EYEPNFSQEV
       550        560        570        580
QRGLQDRGQN QTQRPFFLNV VQAVSQEGAC VYAVSDLRKS GEAAGY         10         20         30         40         50         60
MARGYGATVS LVLLGLGLAL AVIVLAVVLS RHQAPCGPQA FAHAAVAADS KVCSDIGRAI
        70         80         90        100        110        120
LQQQGSPVDA TIAALVCTSV VNPQSMGLGG GVIFTIYNVT TGKVEVINAR ETVPASHAPS
       130        140        150        160        170        180
LLDQCAQALP LGTGAQWIGV PGELRGYAEA HRRHGRLPWA QLFQPTIALL RGGHVVAPVL
       190        200        210        220        230        240
SRFLHNSILR PSLQASTLRQ LFFNGTEPLR PQDPLPWPAL ATTLETVATE GVEVFYTGRL
       250        260        270        280        290        300
GQMLVEDIAK EGSQLTLQDL AKFQPEVVDA LEVPLGDYTL YSPPPPAGGA ILSFILNVLR
       310        320        330        340        350        360
GFNFSTESMA RPEGRVNVYH HLVETLKFAK GQRWRLGDPR SHPKLQNASR DLLGETLAQL
       370        380        390        400        410        420
IRQQIDGRGD HQLSHYSLAE AWGHGTGTSH VSVLGEDGSA VAATSTINTP FGAMVYSPRT
       430        440        450        460        470        480
GIILNNELLD LCERCPRGSG TTPSPVSGDR VGGAPGRCWP PVPGERSPSS MVPSILINKA
       490        500        510        520        530        540
QGSKLVIGGA GGELIISAVA QAIMSKLWLG FDLRAAIAAP ILHVNSKGCV EYEPNFSQEV
       550        560        570        580
QRGLQDRGQN QTQRPFFLNV VQAVSQEGAC VYAVSDLRKS GEAAGY

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P36269-1-unknown	MARGYG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P36269-1-unknown	MARGYG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75949
P36269-1-unknown	MARGYG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75950
P36269-388-unknown	TSHVSV...	388	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P36269-388-unknown	TSHVSV...	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt116194
P36269-388-unknown	TSHVSV...	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt116193
P36269-388-unknown	TSHVSV...	388	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GHGTGT	387	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GHGTGT	387	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92628
...GHGTGT	387	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92627
...EAAGY	586	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EAAGY	586	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71567
...EAAGY	586	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71568

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

P36269: Glutathione hydrolase 5 proenzyme

General Information

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates