TopFIND 4.0

P36406: E3 ubiquitin-protein ligase TRIM23

General Information

Protein names
- E3 ubiquitin-protein ligase TRIM23
- 2.3.2.27
- ADP-ribosylation factor domain-containing protein 1
- GTP-binding protein ARD-1
- RING finger protein 46
- RING-type E3 ubiquitin transferase TRIM23 {ECO:0000305}
- Tripartite motif-containing protein 23
Gene names TRIM23
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P36406

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MATLVVNKLG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL 
        70         80         90        100        110        120 
TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGPIGQY GAAEESIGIS 
       130        140        150        160        170        180 
GESIIRCDED EAHLASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCSQ 
       190        200        210        220        230        240 
HQVHAIEFVC LEEGCQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF 
       250        260        270        280        290        300 
TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT AENARSCIRA YFYDLHETLC 
       310        320        330        340        350        360 
RQEEMALSVV DAHVREKLIW LRQQQEDMTI LLSEVSAACL HCEKTLQQDD CRVVLAKQEI 
       370        380        390        400        410        420 
TRLLETLQKQ QQQFTEVADH IQLDASIPVT FTKDNRVHIG PKMEIRVVTL GLDGAGKTTI 
       430        440        450        460        470        480 
LFKLKQDEFM QPIPTIGFNV ETVEYKNLKF TIWDVGGKHK LRPLWKHYYL NTQAVVFVVD 
       490        500        510        520        530        540 
SSHRDRISEA HSELAKLLTE KELRDALLLI FANKQDVAGA LSVEEITELL SLHKLCCGRS 
       550        560        570    
WYIQGCDARS GMGLYEGLDW LSRQLVAAGV LDVA

Isoforms

- Isoform Beta of E3 ubiquitin-protein ligase TRIM23 - Isoform Gamma of E3 ubiquitin-protein ligase TRIM23

Sequence View

        10         20         30         40         50         60 
MATLVVNKLG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL 
        70         80         90        100        110        120 
TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGPIGQY GAAEESIGIS 
       130        140        150        160        170        180 
GESIIRCDED EAHLASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCSQ 
       190        200        210        220        230        240 
HQVHAIEFVC LEEGCQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF 
       250        260        270        280        290        300 
TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT AENARSCIRA YFYDLHETLC 
       310        320        330        340        350        360 
RQEEMALSVV DAHVREKLIW LRQQQEDMTI LLSEVSAACL HCEKTLQQDD CRVVLAKQEI 
       370        380        390        400        410        420 
TRLLETLQKQ QQQFTEVADH IQLDASIPVT FTKDNRVHIG PKMEIRVVTL GLDGAGKTTI 
       430        440        450        460        470        480 
LFKLKQDEFM QPIPTIGFNV ETVEYKNLKF TIWDVGGKHK LRPLWKHYYL NTQAVVFVVD 
       490        500        510        520        530        540 
SSHRDRISEA HSELAKLLTE KELRDALLLI FANKQDVAGA LSVEEITELL SLHKLCCGRS 
       550        560        570    
WYIQGCDARS GMGLYEGLDW LSRQLVAAGV LDVA         10         20         30         40         50         60 
MATLVVNKLG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL 
        70         80         90        100        110        120 
TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGPIGQY GAAEESIGIS 
       130        140        150        160        170        180 
GESIIRCDED EAHLASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCSQ 
       190        200        210        220        230        240 
HQVHAIEFVC LEEGCQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF 
       250        260        270        280        290        300 
TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT AENARSCIRA YFYDLHETLC 
       310        320        330        340        350        360 
RQEEMALSVV DAHVREKLIW LRQQQEDMTI LLSEVSAACL HCEKTLQQDD CRVVLAKQEI 
       370        380        390        400        410        420 
TRLLETLQKQ QQQFTEVADH IQLDASIPVT FTKDNRVHIG PKMEIRVVTL GLDGAGKTTI 
       430        440        450        460        470        480 
LFKLKQDEFM QPIPTIGFNV ETVEYKNLKF TIWDVGGKHK LRPLWKHYYL NTQAVVFVVD 
       490        500        510        520        530        540 
SSHRDRISEA HSELAKLLTE KELRDALLLI FANKQDVAGA LSVEEITELL SLHKLCCGRS 
       550        560        570    
WYIQGCDARS GMGLYEGLDW LSRQLVAAGV LDVA



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P36406-1-unknown MATLVV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P36406-1-unknown MATLVV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93005
    P36406-1-unknown MATLVV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93006

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VLDVA 574 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)