TopFIND 4.0

P36407: E3 ubiquitin-protein ligase TRIM23

General Information

Protein names
- E3 ubiquitin-protein ligase TRIM23
- 2.3.2.27
- ADP-ribosylation factor domain-containing protein 1
- GTP-binding protein ARD-1
- RING-type E3 ubiquitin transferase TRIM23 {ECO:0000305}
- Tripartite motif-containing protein 23
Gene names Trim23
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P36407

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAALAVNKPG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL 
        70         80         90        100        110        120 
TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGHIGQY GAAEEALGIS 
       130        140        150        160        170        180 
GESIIRCDED EAHVASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCCQ 
       190        200        210        220        230        240 
HQVHAIEFVC LEEACQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF 
       250        260        270        280        290        300 
TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT AENARSCVRA YFSDLHETLC 
       310        320        330        340        350        360 
RQEEMALSVV DAHVREKLIW LRQQQEDMTI LLSQVSTACL HCKTLQQDDC RVVLAKQEIT 
       370        380        390        400        410        420 
RLLETLQKQQ QQFTEVADHI QLDASIPVTF TKDNRVYHGP KMEIRVVTLG LDGAGKTTIL 
       430        440        450        460        470        480 
FKLKQDEFMQ PIPTIGFNVE TVEYKNLKFT IWDVGGKHKL RPLWKHYYLN TQAVVFVVDS 
       490        500        510        520        530        540 
SHRDRISEAH SELAKLLTEK ELRDALLLIF ANKQDVAGAL SVEEITELLS LHKLCCGRSW 
       550        560        570    
YIQGCDARSG MGLYEGLDWL SRQLVAAGVL DVA

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase TRIM23

Sequence View

        10         20         30         40         50         60 
MAALAVNKPG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL 
        70         80         90        100        110        120 
TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGHIGQY GAAEEALGIS 
       130        140        150        160        170        180 
GESIIRCDED EAHVASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCCQ 
       190        200        210        220        230        240 
HQVHAIEFVC LEEACQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF 
       250        260        270        280        290        300 
TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT AENARSCVRA YFSDLHETLC 
       310        320        330        340        350        360 
RQEEMALSVV DAHVREKLIW LRQQQEDMTI LLSQVSTACL HCKTLQQDDC RVVLAKQEIT 
       370        380        390        400        410        420 
RLLETLQKQQ QQFTEVADHI QLDASIPVTF TKDNRVYHGP KMEIRVVTLG LDGAGKTTIL 
       430        440        450        460        470        480 
FKLKQDEFMQ PIPTIGFNVE TVEYKNLKFT IWDVGGKHKL RPLWKHYYLN TQAVVFVVDS 
       490        500        510        520        530        540 
SHRDRISEAH SELAKLLTEK ELRDALLLIF ANKQDVAGAL SVEEITELLS LHKLCCGRSW 
       550        560        570    
YIQGCDARSG MGLYEGLDWL SRQLVAAGVL DVA



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Directness:


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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P36407-1-unknown MAALAV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P36407-1-unknown MAALAV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt193651

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VLDVA 573 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VLDVA 573 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt153597

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)