P36896: Activin receptor type-1B

General Information

Protein names	- Activin receptor type-1B - 2.7.11.30 - Activin receptor type IB - ACTR-IB - Activin receptor-like kinase 4 - ALK-4 - Serine/threonine-protein kinase receptor R2 - SKR2
Gene names	ACVR1B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P36896

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Activin receptor type-1B - Isoform 3 of Activin receptor type-1B - Isoform 4 of Activin receptor type-1B - Isoform 5 of Activin receptor type-1B

Sequence View

        10         20         30         40         50         60
MAESAGASSF FPLVVLLLAG SGGSGPRGVQ ALLCACTSCL QANYTCETDG ACMVSIFNLD
        70         80         90        100        110        120
GMEHHVRTCI PKVELVPAGK PFYCLSSEDL RNTHCCYTDY CNRIDLRVPS GHLKEPEHPS
       130        140        150        160        170        180
MWGPVELVGI IAGPVFLLFL IIIIVFLVIN YHQRVYHNRQ RLDMEDPSCE MCLSKDKTLQ
       190        200        210        220        230        240
DLVYDLSTSG SGSGLPLFVQ RTVARTIVLQ EIIGKGRFGE VWRGRWRGGD VAVKIFSSRE
       250        260        270        280        290        300
ERSWFREAEI YQTVMLRHEN ILGFIAADNK DNGTWTQLWL VSDYHEHGSL FDYLNRYTVT
       310        320        330        340        350        360
IEGMIKLALS AASGLAHLHM EIVGTQGKPG IAHRDLKSKN ILVKKNGMCA IADLGLAVRH
       370        380        390        400        410        420
DAVTDTIDIA PNQRVGTKRY MAPEVLDETI NMKHFDSFKC ADIYALGLVY WEIARRCNSG
       430        440        450        460        470        480
GVHEEYQLPY YDLVPSDPSI EEMRKVVCDQ KLRPNIPNWW QSYEALRVMG KMMRECWYAN
       490        500
GAARLTALRI KKTLSQLSVQ EDVKI         10         20         30         40         50         60
MAESAGASSF FPLVVLLLAG SGGSGPRGVQ ALLCACTSCL QANYTCETDG ACMVSIFNLD
        70         80         90        100        110        120
GMEHHVRTCI PKVELVPAGK PFYCLSSEDL RNTHCCYTDY CNRIDLRVPS GHLKEPEHPS
       130        140        150        160        170        180
MWGPVELVGI IAGPVFLLFL IIIIVFLVIN YHQRVYHNRQ RLDMEDPSCE MCLSKDKTLQ
       190        200        210        220        230        240
DLVYDLSTSG SGSGLPLFVQ RTVARTIVLQ EIIGKGRFGE VWRGRWRGGD VAVKIFSSRE
       250        260        270        280        290        300
ERSWFREAEI YQTVMLRHEN ILGFIAADNK DNGTWTQLWL VSDYHEHGSL FDYLNRYTVT
       310        320        330        340        350        360
IEGMIKLALS AASGLAHLHM EIVGTQGKPG IAHRDLKSKN ILVKKNGMCA IADLGLAVRH
       370        380        390        400        410        420
DAVTDTIDIA PNQRVGTKRY MAPEVLDETI NMKHFDSFKC ADIYALGLVY WEIARRCNSG
       430        440        450        460        470        480
GVHEEYQLPY YDLVPSDPSI EEMRKVVCDQ KLRPNIPNWW QSYEALRVMG KMMRECWYAN
       490        500
GAARLTALRI KKTLSQLSVQ EDVKI         10         20         30         40         50         60
MAESAGASSF FPLVVLLLAG SGGSGPRGVQ ALLCACTSCL QANYTCETDG ACMVSIFNLD
        70         80         90        100        110        120
GMEHHVRTCI PKVELVPAGK PFYCLSSEDL RNTHCCYTDY CNRIDLRVPS GHLKEPEHPS
       130        140        150        160        170        180
MWGPVELVGI IAGPVFLLFL IIIIVFLVIN YHQRVYHNRQ RLDMEDPSCE MCLSKDKTLQ
       190        200        210        220        230        240
DLVYDLSTSG SGSGLPLFVQ RTVARTIVLQ EIIGKGRFGE VWRGRWRGGD VAVKIFSSRE
       250        260        270        280        290        300
ERSWFREAEI YQTVMLRHEN ILGFIAADNK DNGTWTQLWL VSDYHEHGSL FDYLNRYTVT
       310        320        330        340        350        360
IEGMIKLALS AASGLAHLHM EIVGTQGKPG IAHRDLKSKN ILVKKNGMCA IADLGLAVRH
       370        380        390        400        410        420
DAVTDTIDIA PNQRVGTKRY MAPEVLDETI NMKHFDSFKC ADIYALGLVY WEIARRCNSG
       430        440        450        460        470        480
GVHEEYQLPY YDLVPSDPSI EEMRKVVCDQ KLRPNIPNWW QSYEALRVMG KMMRECWYAN
       490        500
GAARLTALRI KKTLSQLSVQ EDVKI         10         20         30         40         50         60
MAESAGASSF FPLVVLLLAG SGGSGPRGVQ ALLCACTSCL QANYTCETDG ACMVSIFNLD
        70         80         90        100        110        120
GMEHHVRTCI PKVELVPAGK PFYCLSSEDL RNTHCCYTDY CNRIDLRVPS GHLKEPEHPS
       130        140        150        160        170        180
MWGPVELVGI IAGPVFLLFL IIIIVFLVIN YHQRVYHNRQ RLDMEDPSCE MCLSKDKTLQ
       190        200        210        220        230        240
DLVYDLSTSG SGSGLPLFVQ RTVARTIVLQ EIIGKGRFGE VWRGRWRGGD VAVKIFSSRE
       250        260        270        280        290        300
ERSWFREAEI YQTVMLRHEN ILGFIAADNK DNGTWTQLWL VSDYHEHGSL FDYLNRYTVT
       310        320        330        340        350        360
IEGMIKLALS AASGLAHLHM EIVGTQGKPG IAHRDLKSKN ILVKKNGMCA IADLGLAVRH
       370        380        390        400        410        420
DAVTDTIDIA PNQRVGTKRY MAPEVLDETI NMKHFDSFKC ADIYALGLVY WEIARRCNSG
       430        440        450        460        470        480
GVHEEYQLPY YDLVPSDPSI EEMRKVVCDQ KLRPNIPNWW QSYEALRVMG KMMRECWYAN
       490        500
GAARLTALRI KKTLSQLSVQ EDVKI

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P36896-1-unknown	MAESAG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66239
P36896-1-unknown	MAESAG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66240
P36896-1-unknown	MAESAG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66241
P36896-24-unknown	SGPRGV...	24	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P36896-24-unknown	SGPRGV...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113594
P36896-24-unknown	SGPRGV...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113595
P36896-24-unknown	SGPRGV...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113596
P36896-53-unknown	MVSIFN...	53	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66242
P36896-53-unknown	MVSIFN...	53	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106711
P36896-53-unknown	MVSIFN...	53	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106712
P36896-53-unknown	MVSIFN...	53	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106713

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EDVKI	505	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EDVKI	505	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61860
...EDVKI	505	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61859

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

P36896: Activin receptor type-1B

General Information

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates