TopFIND 4.0

P36970: Phospholipid hydroperoxide glutathione peroxidase {ECO:0000303|PubMed:7592947}

General Information

Protein names
- Phospholipid hydroperoxide glutathione peroxidase {ECO:0000303|PubMed:7592947}
- PHGPx {ECO:0000303|PubMed:7592947}
- 1.11.1.12 {ECO:0000269|PubMed:1556123}
- Glutathione peroxidase 4 {ECO:0000250|UniProtKB:O70325}
- GPx-4 {ECO:0000250|UniProtKB:O70325}
- GSHPx-4 {ECO:0000250|UniProtKB:O70325}
Gene names Gpx4
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P36970

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSWGRLSRLL KPALLCGALA VPGLAGTMCA SRDDWRCARS MHEFAAKDID GHMVCLDKYR 
        70         80         90        100        110        120 
GCVCIVTNVA SQUGKTDVNY TQLVDLHARY AECGLRILAF PCNQFGRQEP GSNQEIKEFA 
       130        140        150        160        170        180 
AGYNVRFDMY SKICVNGDDA HPLWKWMKVQ PKGRGMLGNA IKWNFTKFLI DKNGCVVKRY 
       190    
GPMEEPQVIE KDLPCYL

Isoforms

- Isoform Cytoplasmic of Phospholipid hydroperoxide glutathione peroxidase, mitochondrial - Isoform Cytoplasmic of Phospholipid hydroperoxide glutathione peroxidase - Isoform Nuclear of Phospholipid hydroperoxide glutathione peroxidase

Sequence View

        10         20         30         40         50         60 
MSWGRLSRLL KPALLCGALA VPGLAGTMCA SRDDWRCARS MHEFAAKDID GHMVCLDKYR 
        70         80         90        100        110        120 
GCVCIVTNVA SQUGKTDVNY TQLVDLHARY AECGLRILAF PCNQFGRQEP GSNQEIKEFA 
       130        140        150        160        170        180 
AGYNVRFDMY SKICVNGDDA HPLWKWMKVQ PKGRGMLGNA IKWNFTKFLI DKNGCVVKRY 
       190    
GPMEEPQVIE KDLPCYL         10         20         30         40         50         60 
MSWGRLSRLL KPALLCGALA VPGLAGTMCA SRDDWRCARS MHEFAAKDID GHMVCLDKYR 
        70         80         90        100        110        120 
GCVCIVTNVA SQUGKTDVNY TQLVDLHARY AECGLRILAF PCNQFGRQEP GSNQEIKEFA 
       130        140        150        160        170        180 
AGYNVRFDMY SKICVNGDDA HPLWKWMKVQ PKGRGMLGNA IKWNFTKFLI DKNGCVVKRY 
       190    
GPMEEPQVIE KDLPCYL         10         20         30         40         50         60 
MSWGRLSRLL KPALLCGALA VPGLAGTMCA SRDDWRCARS MHEFAAKDID GHMVCLDKYR 
        70         80         90        100        110        120 
GCVCIVTNVA SQUGKTDVNY TQLVDLHARY AECGLRILAF PCNQFGRQEP GSNQEIKEFA 
       130        140        150        160        170        180 
AGYNVRFDMY SKICVNGDDA HPLWKWMKVQ PKGRGMLGNA IKWNFTKFLI DKNGCVVKRY 
       190    
GPMEEPQVIE KDLPCYL



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P36970-0-unknown LMSWGR... 0 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P36970-28-unknown MCASRD... 28 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt192711

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LPCYL 197 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LPCYL 197 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt152657

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)