P37040: NADPH--cytochrome P450 reductase {ECO:0000255|HAMAP-Rule:MF_03212}

General Information

Protein names	- NADPH--cytochrome P450 reductase {ECO:0000255\|HAMAP-Rule:MF_03212} - CPR {ECO:0000255\|HAMAP-Rule:MF_03212} - P450R {ECO:0000255\|HAMAP-Rule:MF_03212} - 1.6.2.4 {ECO:0000255\|HAMAP-Rule:MF_03212}
Gene names	Por
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P37040

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGDSHEDTSA TVPEAVAEEV SLFSTTDIVL FSLIVGVLTY WFIFKKKKEE IPEFSKIQTT
        70         80         90        100        110        120
APPVKESSFV EKMKKTGRNI IVFYGSQTGT AEEFANRLSK DAHRYGMRGM SADPEEYDLA
       130        140        150        160        170        180
DLSSLPEIDK SLVVFCMATY GEGDPTDNAQ DFYDWLQETD VDLTGVKFAV FGLGNKTYEH
       190        200        210        220        230        240
FNAMGKYVDQ RLEQLGAQRI FELGLGDDDG NLEEDFITWR EQFWPAVCEF FGVEATGEES
       250        260        270        280        290        300
SIRQYELVVH EDMDTAKVYT GEMGRLKSYE NQKPPFDAKN PFLAAVTTNR KLNQGTERHL
       310        320        330        340        350        360
MHLELDISDS KIRYESGDHV AVYPANDSTL VNQIGEILGA DLDVIMSLNN LDEESNKKHP
       370        380        390        400        410        420
FPCPTTYRTA LTYYLDITNP PRTNVLYELA QYASEPSEQE HLHKMASSSG EGKELYLSWV
       430        440        450        460        470        480
VEARRHILAI LQDYPSLRPP IDHLCELLPR LQARYYSIAS SSKVHPNSVH ICAVAVEYEA
       490        500        510        520        530        540
KSGRVNKGVA TSWLRTKEPA GENGRRALVP MFVRKSQFRL PFKPTTPVIM VGPGTGVAPF
       550        560        570        580        590        600
MGFIQERAWL REQGKEVGET LLYYGCRRSD EDYLYREELA RFHKDGALTQ LNVAFSREQA
       610        620        630        640        650        660
HKVYVQHLLK RDKEHLWKLI HEGGAHIYVC GDARNMAKDV QNTFYDIVAE FGPMEHTQAV
       670
DYVKKLMTKG RYSLDVWS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P37040-2-unknown	MGDSHE...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P37040-2-unknown	MGDSHE...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P37040-2-Acetylation	GDSHED...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P37040-2-Acetylation	GDSHED...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LADLSS	123	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119138
...DFITWR	219	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121022
...YENQKP	273	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121531
...LDVWS	678	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)