TopFIND 4.0

P38135: Medium-chain fatty-acid--CoA ligase {ECO:0000305|PubMed:15213221, ECO:0000305|PubMed:19477415}

General Information

Protein names
- Medium-chain fatty-acid--CoA ligase {ECO:0000305|PubMed:15213221, ECO:0000305|PubMed:19477415}
- 6.2.1.- {ECO:0000269|PubMed:15213221, ECO:0000269|PubMed:19477415}
- Acyl-CoA synthetase {ECO:0000303|PubMed:15213221}
- ACS {ECO:0000303|PubMed:15213221}
- Fatty acyl-CoA synthetase FadK {ECO:0000305}
Gene names fadK
Organism Escherichia coli
Protease Family
Protease ID
Chromosome location
UniProt ID P38135

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MHPTGPHLGP DVLFRESNMK VTLTFNEQRR AAYRQQGLWG DASLADYWQQ TARAMPDKIA 
        70         80         90        100        110        120 
VVDNHGASYT YSALDHAASC LANWMLAKGI ESGDRIAFQL PGWCEFTVIY LACLKIGAVS 
       130        140        150        160        170        180 
VPLLPSWREA ELVWVLNKCQ AKMFFAPTLF KQTRPVDLIL PLQNQLPQLQ QIVGVDKLAP 
       190        200        210        220        230        240 
ATSSLSLSQI IADNTSLTTA ITTHGDELAA VLFTSGTEGL PKGVMLTHNN ILASERAYCA 
       250        260        270        280        290        300 
RLNLTWQDVF MMPAPLGHAT GFLHGVTAPF LIGARSVLLD IFTPDACLAL LEQQRCTCML 
       310        320        330        340        350        360 
GATPFVYDLL NVLEKQPADL SALRFFLCGG TTIPKKVARE CQQRGIKLLS VYGSTESSPH 
       370        380        390        400        410        420 
AVVNLDDPLS RFMHTDGYAA AGVEIKVVDD ARKTLPPGCE GEEASRGPNV FMGYFDEPEL 
       430        440        450        460        470        480 
TARALDEEGW YYSGDLCRMD EAGYIKITGR KKDIIVRGGE NISSREVEDI LLQHPKIHDA 
       490        500        510        520        530        540 
CVVAMSDERL GERSCAYVVL KAPHHSLSLE EVVAFFSRKR VAKYKYPEHI VVIEKLPRTT 
       550        560    
SGKIQKFLLR KDIMRRLTQD VCEEIE

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P38135-1-unknown MHPTGP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IQKFLL 548 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)