TopFIND 4.0

P38207: DNA-(apurinic or apyrimidinic site) lyase 2

General Information

Protein names
- DNA-(apurinic or apyrimidinic site) lyase 2
- 4.2.99.18
- AP endonuclease 2
- Apurinic-apyrimidinic endonuclease 2
Gene names APN2
Organism Saccharomyces cerevisiae
Protease Family
Protease ID
Chromosome location
UniProt ID P38207

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSSSENTLLD GKSENTIRFL TFNVNGIRTF FHYQPFSQMN QSLRSVFDFF RADIITFQEL 
        70         80         90        100        110        120 
KTEKLSISKW GRVDGFYSFI SIPQTRKGYS GVGCWIRIPE KNHPLYHALQ VVKAEEGITG 
       130        140        150        160        170        180 
YLTIKNGKHS AISYRNDVNQ GIGGYDSLDP DLDEKSALEL DSEGRCVMVE LACGIVIISV 
       190        200        210        220        230        240 
YCPANSNSSE EGEMFRLRFL KVLLRRVRNL DKIGKKIVLM GDVNVCRDLI DSADTLEQFS 
       250        260        270        280        290        300 
IPITDPMGGT KLEAQYRDKA IQFIINPDTP HRRIFNQILA DSLLPDASKR GILIDTTRLI 
       310        320        330        340        350        360 
QTRNRLKMYT VWNMLKNLRP SNYGSRIDFI LVSLKLERCI KAADILPDIL GSDHCPVYSD 
       370        380        390        400        410        420 
LDILDDRIEP GTTQVPIPKF EARYKYNLRN HNVLEMFAKK DTNKESNKQK YCVSKVMNTK 
       430        440        450        460        470        480 
KNSNIKNKSL DSFFQKVNGE KDDRIKESSE IPQQAKKRIS TPKLNFKDVF GKPPLCRHGE 
       490        500        510        520    
ESMLKTSKTS ANPGRKFWIC KRSRGDSNNT ESSCGFFQWV 

Isoforms



Sequence View



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Biological System:


Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P38207-1-unknown MSSSEN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...FFQWV 520 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)