TopFIND 4.0

P39098: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

General Information

Protein names
- Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB
- 3.2.1.113 {ECO:0000250|UniProtKB:P32906}
- Mannosidase alpha class 1A member 2
- Processing alpha-1,2-mannosidase IB
- Alpha-1,2-mannosidase IB
Gene names Man1a2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P39098

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTTPALLPLS GRRIPPLNLG PPSFPHHRAT LRLSEKFILL LILSAFITLC FGAFFFLPDS 
        70         80         90        100        110        120 
SKHKRFDLGL EDVLIPHVDA GKGAKNPGVF LIHGPDEHRH REEEERLRNK IRADHEKALE 
       130        140        150        160        170        180 
EAKEKLRKSR EEIRAEIQTE KNKVAQAMKT KETRVLPPVP VPQRVGVSGG DPEDMEIKKK 
       190        200        210        220        230        240 
RDKIKEMMKH AWDNYRTYGW GHNELRPIAR KGHSTNIFGS SQMGATIVDA LDTLYIMGLH 
       250        260        270        280        290        300 
DEFMDGQRWI EENLDFSVNS EVSVFEVNIR FIGGLLAAYY LSGEEIFKTK AVQLAEKLLP 
       310        320        330        340        350        360 
AFNTPTGIPW AMVNLKSGVG RNWGWASAGS SILAEFGTLH MEFVHLSYLT GDLTYYNKVM 
       370        380        390        400        410        420 
HIRKLLQKME RPNGLYPNYL NPRTGRWGQY HTSVGGLGDS FYEYLLKAWL MSDKTDHEAR 
       430        440        450        460        470        480 
RMYDDAVEAI EKHLIKKSRG GLVFIGEWKN GHLERKMGHL ACFAGGMFAL GADGSRKDKA 
       490        500        510        520        530        540 
GHYLELGAEI ARTCHESYDR TALKLGPESF KFDGAVEAVA VRQAEKYYIL RPEVIETYWY 
       550        560        570        580        590        600 
LWRFTHDPRY RQWGWEAALA IEKSCRVSGG FSGVKDVYAP TPVHDDVQQS FFLAETLKYL 
       610        620        630        640    
YLLFSGDDLL PLDHWVFNTE AHPLPVLRLA NSTLSGNPAV R

Isoforms

- Isoform 2 of Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

Sequence View

        10         20         30         40         50         60 
MTTPALLPLS GRRIPPLNLG PPSFPHHRAT LRLSEKFILL LILSAFITLC FGAFFFLPDS 
        70         80         90        100        110        120 
SKHKRFDLGL EDVLIPHVDA GKGAKNPGVF LIHGPDEHRH REEEERLRNK IRADHEKALE 
       130        140        150        160        170        180 
EAKEKLRKSR EEIRAEIQTE KNKVAQAMKT KETRVLPPVP VPQRVGVSGG DPEDMEIKKK 
       190        200        210        220        230        240 
RDKIKEMMKH AWDNYRTYGW GHNELRPIAR KGHSTNIFGS SQMGATIVDA LDTLYIMGLH 
       250        260        270        280        290        300 
DEFMDGQRWI EENLDFSVNS EVSVFEVNIR FIGGLLAAYY LSGEEIFKTK AVQLAEKLLP 
       310        320        330        340        350        360 
AFNTPTGIPW AMVNLKSGVG RNWGWASAGS SILAEFGTLH MEFVHLSYLT GDLTYYNKVM 
       370        380        390        400        410        420 
HIRKLLQKME RPNGLYPNYL NPRTGRWGQY HTSVGGLGDS FYEYLLKAWL MSDKTDHEAR 
       430        440        450        460        470        480 
RMYDDAVEAI EKHLIKKSRG GLVFIGEWKN GHLERKMGHL ACFAGGMFAL GADGSRKDKA 
       490        500        510        520        530        540 
GHYLELGAEI ARTCHESYDR TALKLGPESF KFDGAVEAVA VRQAEKYYIL RPEVIETYWY 
       550        560        570        580        590        600 
LWRFTHDPRY RQWGWEAALA IEKSCRVSGG FSGVKDVYAP TPVHDDVQQS FFLAETLKYL 
       610        620        630        640    
YLLFSGDDLL PLDHWVFNTE AHPLPVLRLA NSTLSGNPAV R



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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NPAVR 641 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...NPAVR 641 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt75827

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)