TopFIND 4.0

P39429: TNF receptor-associated factor 2

General Information

Protein names
- TNF receptor-associated factor 2
- 2.3.2.27
- E3 ubiquitin-protein ligase TRAF2
- RING-type E3 ubiquitin transferase TRAF2 {ECO:0000305}
Gene names Traf2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P39429

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAASVTSPG SLELLQPGFS KTLLGTRLEA KYLCSACKNI LRRPFQAQCG HRYCSFCLTS 
        70         80         90        100        110        120 
ILSSGPQNCA ACVYEGLYEE GISILESSSA FPDNAARREV ESLPAVCPND GCTWKGTLKE 
       130        140        150        160        170        180 
YESCHEGLCP FLLTECPACK GLVRLSEKEH HTEQECPKRS LSCQHCRAPC SHVDLEVHYE 
       190        200        210        220        230        240 
VCPKFPLTCD GCGKKKIPRE TFQDHVRACS KCRVLCRFHT VGCSEMVETE NLQDHELQRL 
       250        260        270        280        290        300 
REHLALLLSS FLEAQASPGT LNQVGPELLQ RCQILEQKIA TFENIVCVLN REVERVAVTA 
       310        320        330        340        350        360 
EACSRQHRLD QDKIEALSNK VQQLERSIGL KDLAMADLEQ KVSELEVSTY DGVFIWKISD 
       370        380        390        400        410        420 
FTRKRQEAVA GRTPAIFSPA FYTSRYGYKM CLRVYLNGDG TGRGTHLSLF FVVMKGPNDA 
       430        440        450        460        470        480 
LLQWPFNQKV TLMLLDHNNR EHVIDAFRPD VTSSSFQRPV SDMNIASGCP LFCPVSKMEA 
       490        500    
KNSYVRDDAI FIKAIVDLTG L

Isoforms

- Isoform 2 of TNF receptor-associated factor 2

Sequence View

        10         20         30         40         50         60 
MAAASVTSPG SLELLQPGFS KTLLGTRLEA KYLCSACKNI LRRPFQAQCG HRYCSFCLTS 
        70         80         90        100        110        120 
ILSSGPQNCA ACVYEGLYEE GISILESSSA FPDNAARREV ESLPAVCPND GCTWKGTLKE 
       130        140        150        160        170        180 
YESCHEGLCP FLLTECPACK GLVRLSEKEH HTEQECPKRS LSCQHCRAPC SHVDLEVHYE 
       190        200        210        220        230        240 
VCPKFPLTCD GCGKKKIPRE TFQDHVRACS KCRVLCRFHT VGCSEMVETE NLQDHELQRL 
       250        260        270        280        290        300 
REHLALLLSS FLEAQASPGT LNQVGPELLQ RCQILEQKIA TFENIVCVLN REVERVAVTA 
       310        320        330        340        350        360 
EACSRQHRLD QDKIEALSNK VQQLERSIGL KDLAMADLEQ KVSELEVSTY DGVFIWKISD 
       370        380        390        400        410        420 
FTRKRQEAVA GRTPAIFSPA FYTSRYGYKM CLRVYLNGDG TGRGTHLSLF FVVMKGPNDA 
       430        440        450        460        470        480 
LLQWPFNQKV TLMLLDHNNR EHVIDAFRPD VTSSSFQRPV SDMNIASGCP LFCPVSKMEA 
       490        500    
KNSYVRDDAI FIKAIVDLTG L



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Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DLTGL 501 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...DLTGL 501 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt88563

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)