TopFIND 4.0

P39538: Ubiquitin carboxyl-terminal hydrolase 12

General Information

Protein names
- Ubiquitin carboxyl-terminal hydrolase 12
- 3.4.19.12
- Deubiquitinating enzyme 12
- Ubiquitin thioesterase 12
- Ubiquitin-specific-processing protease 12
Gene names UBP12
Organism Saccharomyces cerevisiae
Protease Family C19.103
Protease ID C19.103
Chromosome location
UniProt ID P39538

1

N-termini

1

C-termini

0

Cleavages

1

Substrates

Sequence

        10         20         30         40         50         60 
MGSSDVSSRE CSLVYNEDPD FTDGTTPCDR LGVDLMNVLD DKDEIKQESV PVSDREIEDT 
        70         80         90        100        110        120 
ESDASAVSSF ASANELIAEP HAASETNLGT NGQDGRNVLE QQRDVVARLI EENKETQKEG 
       130        140        150        160        170        180 
DKVCIVPKVW YDKFFDPDVT DPEDIGPINT RMICRDFENF VLEDYNRCPY LSIAEPVFNF 
       190        200        210        220        230        240 
LSEIYGMTSG SYPVVTNLVI NQTTGELETE YNKWFFRLHY LTEKQDGRKR RHGQDDSIMY 
       250        260        270        280        290        300 
LSMSALNLVR DLVEKSMNLF FEKADHLDVN AVDFKIWFVS EGSDIATDSN VSTFLNSSYE 
       310        320        330        340        350        360 
ITPLQFLELP IKKLLIPDMF ENRLDKITSN PSDLVIEIKP IEGNHHWPSN YFAYNKLEPA 
       370        380        390        400        410        420 
SGTTGLVNLG NTCYMNSALQ CLVHIPQLRD YFLYDGYEDE INEENPLGYH GYVARAFSDL 
       430        440        450        460        470        480 
VQKLFQNRMS IMQRNAAFPP SMFKSTIGHF NSMFSGYMQQ DSQEFLAFLL DSLHEDLNRI 
       490        500        510        520        530        540 
IKKEYTEKPS LSPGDDVNDW NVVKKLADDT WEMHLKRNCS VITDLFVGMY KSTLYCPECQ 
       550        560        570        580        590        600 
NVSITFDPYN DVTLPLPVDT VWDKTIKIFP MNSPPLLLEV ELSKSSTYMD LKNYVGKMSG 
       610        620        630        640        650        660 
LDPNTLFGCE IFSNQIYVNY ESTESNAQFL TLQELIKPAD DVIFYELPVT NDNEVIVPVL 
       670        680        690        700        710        720 
NTRIEKGYKN AMLFGVPFFI TLKEDELNNP GAIRMKLQNR FVHLSGGYIP FPEPVGNRTD 
       730        740        750        760        770        780 
FADAFPLLVE KYPDVEFEQY KDILQYTSIK VTDKDKSFFS IKILSVEKEQ QFASNNRTGP 
       790        800        810        820        830        840 
NFWTPISQLN LDKATDIDDK LEDVVKDIYN YSSLVDCAEG VLMQVDDEGD TEGSEAKNFS 
       850        860        870        880        890        900 
KPFQSGDDEE NKETVTNNEN VNNTNDRDED MELTDDVEED ASTEPELTDK PEALDKIKDS 
       910        920        930        940        950        960 
LTSTPFAILS MNDIIVCEWS ELGSNEAFSD DKIYNWENPA TLPNKELENA KLERSNAKER 
       970        980        990       1000       1010       1020 
TITLDDCLQL FSKPEILGLT DSWYCPTCKE HRQATKQIQL WNTPDILLIH LKRFESQRSF 
      1030       1040       1050       1060       1070       1080 
SDKIDATVNF PITDLDLSRY VVYKDDPRGL IYDLYAVDNH YGGLGGGHYT AYVKNFADNK 
      1090       1100       1110       1120       1130       1140 
WYYFDDSRVT ETAPENSIAG SAYLLFYIRR HKDGNGLGSS KLQEIIQKSR HGYDERIKKI 
      1150       1160       1170       1180       1190       1200 
YDEQMKLYEF NKTDEEEDVS DDMIECNEDV QAPEYSNRSL EVGHIETQDC NDEDDNDDGE 
      1210       1220       1230       1240       1250    
RTNSGRRKLR LLKKVYKNNS GLGSSSTSEI SEGCPENEVA DLNLKNGVTL ESPE

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 1 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P39538-1-unknown MGSSDV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LESPE 1254 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates