TopFIND 4.0

P40126: L-dopachrome tautomerase

General Information

Protein names
- L-dopachrome tautomerase
- DCT
- DT
- 5.3.3.12
- L-dopachrome Delta-isomerase
- Tyrosinase-related protein 2
- TRP-2
- TRP2
Gene names DCT
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P40126

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSPLWWGFLL SCLGCKILPG AQGQFPRVCM TVDSLVNKEC CPRLGAESAN VCGSQQGRGQ 
        70         80         90        100        110        120 
CTEVRADTRP WSGPYILRNQ DDRELWPRKF FHRTCKCTGN FAGYNCGDCK FGWTGPNCER 
       130        140        150        160        170        180 
KKPPVIRQNI HSLSPQEREQ FLGALDLAKK RVHPDYVITT QHWLGLLGPN GTQPQFANCS 
       190        200        210        220        230        240 
VYDFFVWLHY YSVRDTLLGP GRPYRAIDFS HQGPAFVTWH RYHLLCLERD LQRLIGNESF 
       250        260        270        280        290        300 
ALPYWNFATG RNECDVCTDQ LFGAARPDDP TLISRNSRFS SWETVCDSLD DYNHLVTLCN 
       310        320        330        340        350        360 
GTYEGLLRRN QMGRNSMKLP TLKDIRDCLS LQKFDNPPFF QNSTFSFRNA LEGFDKADGT 
       370        380        390        400        410        420 
LDSQVMSLHN LVHSFLNGTN ALPHSAANDP IFVVLHSFTD AIFDEWMKRF NPPADAWPQE 
       430        440        450        460        470        480 
LAPIGHNRMY NMVPFFPPVT NEELFLTSDQ LGYSYAIDLP VSVEETPGWP TTLLVVMGTL 
       490        500        510    
VALVGLFVLL AFLQYRRLRK GYTPLMETHL SSKRYTEEA

Isoforms

- Isoform 2 of L-dopachrome tautomerase

Sequence View

        10         20         30         40         50         60 
MSPLWWGFLL SCLGCKILPG AQGQFPRVCM TVDSLVNKEC CPRLGAESAN VCGSQQGRGQ 
        70         80         90        100        110        120 
CTEVRADTRP WSGPYILRNQ DDRELWPRKF FHRTCKCTGN FAGYNCGDCK FGWTGPNCER 
       130        140        150        160        170        180 
KKPPVIRQNI HSLSPQEREQ FLGALDLAKK RVHPDYVITT QHWLGLLGPN GTQPQFANCS 
       190        200        210        220        230        240 
VYDFFVWLHY YSVRDTLLGP GRPYRAIDFS HQGPAFVTWH RYHLLCLERD LQRLIGNESF 
       250        260        270        280        290        300 
ALPYWNFATG RNECDVCTDQ LFGAARPDDP TLISRNSRFS SWETVCDSLD DYNHLVTLCN 
       310        320        330        340        350        360 
GTYEGLLRRN QMGRNSMKLP TLKDIRDCLS LQKFDNPPFF QNSTFSFRNA LEGFDKADGT 
       370        380        390        400        410        420 
LDSQVMSLHN LVHSFLNGTN ALPHSAANDP IFVVLHSFTD AIFDEWMKRF NPPADAWPQE 
       430        440        450        460        470        480 
LAPIGHNRMY NMVPFFPPVT NEELFLTSDQ LGYSYAIDLP VSVEETPGWP TTLLVVMGTL 
       490        500        510    
VALVGLFVLL AFLQYRRLRK GYTPLMETHL SSKRYTEEA



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P40126-1-unknown MSPLWW... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93497
    P40126-24-unknown QFPRVC... 24 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P40126-24-unknown QFPRVC... 24 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113689

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...YTEEA 519 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...YTEEA 519 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt89115

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)