P40495: Homoisocitrate dehydrogenase, mitochondrial
| Protein names | - Homoisocitrate dehydrogenase, mitochondrial - HIcDH - 1.1.1.87 |
|---|---|
| Gene names | LYS12 |
| Organism | Saccharomyces cerevisiae |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P40495 |
3
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MFRSVATRLS ACRGLASNAA RKSLTIGLIP GDGIGKEVIP AGKQVLENLN SKHGLSFNFI
70 80 90 100 110 120
DLYAGFQTFQ ETGKALPDET VKVLKEQCQG ALFGAVQSPT TKVEGYSSPI VALRREMGLF
130 140 150 160 170 180
ANVRPVKSVE GEKGKPIDMV IVRENTEDLY IKIEKTYIDK ATGTRVADAT KRISEIATRR
190 200 210 220 230 240
IATIALDIAL KRLQTRGQAT LTVTHKSNVL SQSDGLFREI CKEVYESNKD KYGQIKYNEQ
250 260 270 280 290 300
IVDSMVYRLF REPQCFDVIV APNLYGDILS DGAAALVGSL GVVPSANVGP EIVIGEPCHG
310 320 330 340 350 360
SAPDIAGKGI ANPIATIRST ALMLEFLGHN EAAQDIYKAV DANLREGSIK TPDLGGKAST
370
QQVVDDVLSR L
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P40495-15-unknown | LASNAA... | 15 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32139 | |||
| P40495-15-unknown | LASNAA... | 15 | unknown | Voegtle FN. et al.: Global Analysis of the Mitochondrial N-Proteome... | 19837041 | ||||
| P40495-16-unknown | ASNAAR... | 16 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32006 | |||
| P40495-16-unknown | ASNAAR... | 16 | unknown | Voegtle FN. et al.: Global Analysis of the Mitochondrial N-Proteome... | 19837041 | ||||
| P40495-23-unknown | SLTIGL... | 23 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...SACRGL | 14 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32139 | |||
| ...ACRGLA | 15 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32006 | |||
| ...VLSRL | 371 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MPPB_YEAST | 14 | CRGL.|.LASN | inferred from experiment | unknown | MEROPS | Meisinger C | Vogtle FN et al.:Global analysis of the mitochon... (M24.026) | 19837041, |
| ICP55_YEAST | 15 | RGLA.|.ASNA | inferred from experiment | unknown | MEROPS | Meisinger C | Vogtle FN et al.:Global analysis of the mitochon... (M24.026) | 19837041, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|