P41047: Tumor necrosis factor ligand superfamily member 6

General Information

Protein names	- Tumor necrosis factor ligand superfamily member 6 - CD95 ligand - CD95-L - Fas antigen ligand - Fas ligand - FasL - CD178 - Tumor necrosis factor ligand superfamily member 6, membrane form - Tumor necrosis factor ligand superfamily member 6, soluble form - Receptor-binding FasL ectodomain - Soluble Fas ligand - sFasL - ADAM10-processed FasL form - APL - FasL intracellular domain - FasL ICD - SPPL2A-processed FasL form - SPA
Gene names	Faslg
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P41047

6 N-termini

6 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MQQPMNYPCP QIFWVDSSAT SSWAPPGSVF PCPSCGPRGP DQRRPPPPPP PVSPLPPPSQ
        70         80         90        100        110        120
PLPLPPLTPL KKKDHNTNLW LPVVFFMVLV ALVGMGLGMY QLFHLQKELA ELREFTNQSL
       130        140        150        160        170        180
KVSSFEKQIA NPSTPSEKKE PRSVAHLTGN PHSRSIPLEW EDTYGTALIS GVKYKKGGLV
       190        200        210        220        230        240
INETGLYFVY SKVYFRGQSC NNQPLNHKVY MRNSKYPEDL VLMEEKRLNY CTTGQIWAHS
       250        260        270
SYLGAVFNLT SADHLYVNIS QLSLINFEES KTFFGLYKL

Isoforms

- Isoform FasLS of Tumor necrosis factor ligand superfamily member 6

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 6 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P41047-1-unknown	MQQPMN...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P41047-109-unknown	LAELRE...	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34447
P41047-112-unknown	LREFTN...	112	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34448
P41047-120-unknown	LKVSSF...	120	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34449
P41047-128-unknown	QIANPS...	128	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P41047-128-unknown	QIANPS...	128	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P41047-211-unknown	MRNSKY...	211	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92603

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NTNLWL	80	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HLQKEL	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34447
...KELAEL	111	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34448
...FTNQSL	119	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34449
...SSFEKQ	127	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GLYKL	279	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GLYKL	279	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88221

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP7_MOUSE	108	QKEL.\|.LAEL	inferred from experiment	unknown	MEROPS	Matrisian LM	Vargo-Gogola T et al.:Identification of novel matrix ... (M10.008)	12464266,
MMP7_MOUSE	111	LAEL.\|.LREF	inferred from experiment	unknown	MEROPS	Matrisian LM	Vargo-Gogola T et al.:Identification of novel matrix ... (M10.008)	12464266,
MMP7_MOUSE	119	NQSL.\|.LKVS	inferred from experiment	unknown	MEROPS	Matrisian LM	Vargo-Gogola T et al.:Identification of novel matrix ... (M10.008)	12464266,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)