P41235: Hepatocyte nuclear factor 4-alpha

General Information

Protein names	- Hepatocyte nuclear factor 4-alpha - HNF-4-alpha - Nuclear receptor subfamily 2 group A member 1 - Transcription factor 14 - TCF-14 - Transcription factor HNF-4
Gene names	HNF4A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P41235

1 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA PNSLGVSALC
        70         80         90        100        110        120
AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC
       130        140        150        160        170        180
FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSRQITSPVS GINGDIRAKK
       190        200        210        220        230        240
IASIADVCES MKEQLLVLVE WAKYIPAFCE LPLDDQVALL RAHAGEHLLL GATKRSMVFK
       250        260        270        280        290        300
DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYAYLK AIIFFDPDAK
       310        320        330        340        350        360
GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL
       370        380        390        400        410        420
FGMAKIDNLL QEMLLGGSPS DAPHAHHPLH PHLMQEHMGT NVIVANTMPT HLSNGQMCEW
       430        440        450        460        470
PRPRGQAATP ETPQPSPPGG SGSEPYKLLP GAVATIVKPL SAIPQPTITK QEVI

Isoforms

- Isoform HNF4-Alpha-2 of Hepatocyte nuclear factor 4-alpha - Isoform HNF4-Alpha-3 of Hepatocyte nuclear factor 4-alpha - Isoform HNF4-Alpha-4 of Hepatocyte nuclear factor 4-alpha - Isoform HNF4-Alpha-7 of Hepatocyte nuclear factor 4-alpha - Isoform HNF4-Alpha-8 of Hepatocyte nuclear factor 4-alpha - Isoform HNF4-Alpha-9 of Hepatocyte nuclear factor 4-alpha

Sequence View

        10         20         30         40         50         60
MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA PNSLGVSALC
        70         80         90        100        110        120
AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC
       130        140        150        160        170        180
FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSRQITSPVS GINGDIRAKK
       190        200        210        220        230        240
IASIADVCES MKEQLLVLVE WAKYIPAFCE LPLDDQVALL RAHAGEHLLL GATKRSMVFK
       250        260        270        280        290        300
DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYAYLK AIIFFDPDAK
       310        320        330        340        350        360
GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL
       370        380        390        400        410        420
FGMAKIDNLL QEMLLGGSPS DAPHAHHPLH PHLMQEHMGT NVIVANTMPT HLSNGQMCEW
       430        440        450        460        470
PRPRGQAATP ETPQPSPPGG SGSEPYKLLP GAVATIVKPL SAIPQPTITK QEVI         10         20         30         40         50         60
MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA PNSLGVSALC
        70         80         90        100        110        120
AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC
       130        140        150        160        170        180
FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSRQITSPVS GINGDIRAKK
       190        200        210        220        230        240
IASIADVCES MKEQLLVLVE WAKYIPAFCE LPLDDQVALL RAHAGEHLLL GATKRSMVFK
       250        260        270        280        290        300
DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYAYLK AIIFFDPDAK
       310        320        330        340        350        360
GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL
       370        380        390        400        410        420
FGMAKIDNLL QEMLLGGSPS DAPHAHHPLH PHLMQEHMGT NVIVANTMPT HLSNGQMCEW
       430        440        450        460        470
PRPRGQAATP ETPQPSPPGG SGSEPYKLLP GAVATIVKPL SAIPQPTITK QEVI         10         20         30         40         50         60
MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA PNSLGVSALC
        70         80         90        100        110        120
AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC
       130        140        150        160        170        180
FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSRQITSPVS GINGDIRAKK
       190        200        210        220        230        240
IASIADVCES MKEQLLVLVE WAKYIPAFCE LPLDDQVALL RAHAGEHLLL GATKRSMVFK
       250        260        270        280        290        300
DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYAYLK AIIFFDPDAK
       310        320        330        340        350        360
GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL
       370        380        390        400        410        420
FGMAKIDNLL QEMLLGGSPS DAPHAHHPLH PHLMQEHMGT NVIVANTMPT HLSNGQMCEW
       430        440        450        460        470
PRPRGQAATP ETPQPSPPGG SGSEPYKLLP GAVATIVKPL SAIPQPTITK QEVI         10         20         30         40         50         60
MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA PNSLGVSALC
        70         80         90        100        110        120
AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC
       130        140        150        160        170        180
FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSRQITSPVS GINGDIRAKK
       190        200        210        220        230        240
IASIADVCES MKEQLLVLVE WAKYIPAFCE LPLDDQVALL RAHAGEHLLL GATKRSMVFK
       250        260        270        280        290        300
DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYAYLK AIIFFDPDAK
       310        320        330        340        350        360
GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL
       370        380        390        400        410        420
FGMAKIDNLL QEMLLGGSPS DAPHAHHPLH PHLMQEHMGT NVIVANTMPT HLSNGQMCEW
       430        440        450        460        470
PRPRGQAATP ETPQPSPPGG SGSEPYKLLP GAVATIVKPL SAIPQPTITK QEVI         10         20         30         40         50         60
MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA PNSLGVSALC
        70         80         90        100        110        120
AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC
       130        140        150        160        170        180
FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSRQITSPVS GINGDIRAKK
       190        200        210        220        230        240
IASIADVCES MKEQLLVLVE WAKYIPAFCE LPLDDQVALL RAHAGEHLLL GATKRSMVFK
       250        260        270        280        290        300
DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYAYLK AIIFFDPDAK
       310        320        330        340        350        360
GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL
       370        380        390        400        410        420
FGMAKIDNLL QEMLLGGSPS DAPHAHHPLH PHLMQEHMGT NVIVANTMPT HLSNGQMCEW
       430        440        450        460        470
PRPRGQAATP ETPQPSPPGG SGSEPYKLLP GAVATIVKPL SAIPQPTITK QEVI         10         20         30         40         50         60
MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA PNSLGVSALC
        70         80         90        100        110        120
AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC
       130        140        150        160        170        180
FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSRQITSPVS GINGDIRAKK
       190        200        210        220        230        240
IASIADVCES MKEQLLVLVE WAKYIPAFCE LPLDDQVALL RAHAGEHLLL GATKRSMVFK
       250        260        270        280        290        300
DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYAYLK AIIFFDPDAK
       310        320        330        340        350        360
GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL
       370        380        390        400        410        420
FGMAKIDNLL QEMLLGGSPS DAPHAHHPLH PHLMQEHMGT NVIVANTMPT HLSNGQMCEW
       430        440        450        460        470
PRPRGQAATP ETPQPSPPGG SGSEPYKLLP GAVATIVKPL SAIPQPTITK QEVI

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P41235-1-unknown	MRLSKT...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P41235-1-unknown	MRLSKT...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77132
P41235-1-unknown	MRLSKT...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77133
P41235-1-unknown	MRLSKT...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77134

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KQEVI	474	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KQEVI	474	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72754
...KQEVI	474	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72753
...KQEVI	474	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72750
...KQEVI	474	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72752

TopFIND

P41235: Hepatocyte nuclear factor 4-alpha

General Information

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates