P41240: Tyrosine-protein kinase CSK

General Information

Protein names	- Tyrosine-protein kinase CSK - 2.7.10.2 {ECO:0000269\|PubMed:1639064, ECO:0000269\|PubMed:7683130, ECO:0000269\|PubMed:9281320} - C-Src kinase - Protein-tyrosine kinase CYL
Gene names	CSK
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P41240

3 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSAIQAAWPS GTECIAKYNF HGTAEQDLPF CKGDVLTIVA VTKDPNWYKA KNKVGREGII
        70         80         90        100        110        120
PANYVQKREG VKAGTKLSLM PWFHGKITRE QAERLLYPPE TGLFLVREST NYPGDYTLCV
       130        140        150        160        170        180
SCDGKVEHYR IMYHASKLSI DEEVYFENLM QLVEHYTSDA DGLCTRLIKP KVMEGTVAAQ
       190        200        210        220        230        240
DEFYRSGWAL NMKELKLLQT IGKGEFGDVM LGDYRGNKVA VKCIKNDATA QAFLAEASVM
       250        260        270        280        290        300
TQLRHSNLVQ LLGVIVEEKG GLYIVTEYMA KGSLVDYLRS RGRSVLGGDC LLKFSLDVCE
       310        320        330        340        350        360
AMEYLEGNNF VHRDLAARNV LVSEDNVAKV SDFGLTKEAS STQDTGKLPV KWTAPEALRE
       370        380        390        400        410        420
KKFSTKSDVW SFGILLWEIY SFGRVPYPRI PLKDVVPRVE KGYKMDAPDG CPPAVYEVMK
       430        440        450
NCWHLDAAMR PSFLQLREQL EHIKTHELHL

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
P41240-2-unknown	MSAIQA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P41240-2-Acetylation	SAIQAA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P41240-2-Acetylation	SAIQAA...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P41240-80-unknown	MPWFHG...	80		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000457497

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IPANYV	64	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454640
...VRESTN	110	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457714
...EVYFEN	147	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457497
...HELHL	450	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)