TopFIND 4.0

P41438: Folate transporter 1

General Information

Protein names
- Folate transporter 1
- Intestinal folate carrier 1
- IFC-1
- Reduced folate carrier 1
- RFC-1
- RFC1
- Solute carrier family 19 member 1
Gene names Slc19a1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P41438

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVPTGQVAEK QAYEEPRQDH ELKSWRCLVF YLCFFGFMAQ LRPGESFITP FLLERKFTKE 
        70         80         90        100        110        120 
QVTNEIIPML PYSHLAVLVP VFLLTDYLRY KPVLVLQCLS FVCVWLLLLL GTSVVHMQLM 
       130        140        150        160        170        180 
EVFYSVTMAA RIAYSSYIFS LVHPSRYQRM ASYSRAAVLL GVFISSVLGQ ALVTVGHIST 
       190        200        210        220        230        240 
YTLNCVSLGF ILFSLVLSLF LKRPKRSLFF NRSTLARGAL PCELDQMHPG PDRPETRKLD 
       250        260        270        280        290        300 
RMLGTCRDSF LVRMLSELVE NARQPQLRLW CLWWVFNSSG YYLITYYVHV LWRSTDSSLS 
       310        320        330        340        350        360 
YNGAVDAAST LLSAITSFSA GFLSIRWTLW SKLVIAGVIA IQASLVFCMF QIRDIWVCYV 
       370        380        390        400        410        420 
TFVLFRGAYQ FLVPIATFQI ASSLSKELCA LVFGINTFLA TALKTCITLV VSDKRGLGLQ 
       430        440        450        460        470        480 
VRDQFRIYFI YFLMLSITCF AWAGLDGLRY CQRGRHQPLA QAQELRSPLE TSVQAISLQD 
       490        500        510    
GDLRGPQPSA PQLLSEDGME DDRGDLRVEA KA

Isoforms

- Isoform 2 of Folate transporter 1 - Isoform 3 of Folate transporter 1 - Isoform 2 of Reduced folate transporter - Isoform 3 of Reduced folate transporter

Sequence View

        10         20         30         40         50         60 
MVPTGQVAEK QAYEEPRQDH ELKSWRCLVF YLCFFGFMAQ LRPGESFITP FLLERKFTKE 
        70         80         90        100        110        120 
QVTNEIIPML PYSHLAVLVP VFLLTDYLRY KPVLVLQCLS FVCVWLLLLL GTSVVHMQLM 
       130        140        150        160        170        180 
EVFYSVTMAA RIAYSSYIFS LVHPSRYQRM ASYSRAAVLL GVFISSVLGQ ALVTVGHIST 
       190        200        210        220        230        240 
YTLNCVSLGF ILFSLVLSLF LKRPKRSLFF NRSTLARGAL PCELDQMHPG PDRPETRKLD 
       250        260        270        280        290        300 
RMLGTCRDSF LVRMLSELVE NARQPQLRLW CLWWVFNSSG YYLITYYVHV LWRSTDSSLS 
       310        320        330        340        350        360 
YNGAVDAAST LLSAITSFSA GFLSIRWTLW SKLVIAGVIA IQASLVFCMF QIRDIWVCYV 
       370        380        390        400        410        420 
TFVLFRGAYQ FLVPIATFQI ASSLSKELCA LVFGINTFLA TALKTCITLV VSDKRGLGLQ 
       430        440        450        460        470        480 
VRDQFRIYFI YFLMLSITCF AWAGLDGLRY CQRGRHQPLA QAQELRSPLE TSVQAISLQD 
       490        500        510    
GDLRGPQPSA PQLLSEDGME DDRGDLRVEA KA         10         20         30         40         50         60 
MVPTGQVAEK QAYEEPRQDH ELKSWRCLVF YLCFFGFMAQ LRPGESFITP FLLERKFTKE 
        70         80         90        100        110        120 
QVTNEIIPML PYSHLAVLVP VFLLTDYLRY KPVLVLQCLS FVCVWLLLLL GTSVVHMQLM 
       130        140        150        160        170        180 
EVFYSVTMAA RIAYSSYIFS LVHPSRYQRM ASYSRAAVLL GVFISSVLGQ ALVTVGHIST 
       190        200        210        220        230        240 
YTLNCVSLGF ILFSLVLSLF LKRPKRSLFF NRSTLARGAL PCELDQMHPG PDRPETRKLD 
       250        260        270        280        290        300 
RMLGTCRDSF LVRMLSELVE NARQPQLRLW CLWWVFNSSG YYLITYYVHV LWRSTDSSLS 
       310        320        330        340        350        360 
YNGAVDAAST LLSAITSFSA GFLSIRWTLW SKLVIAGVIA IQASLVFCMF QIRDIWVCYV 
       370        380        390        400        410        420 
TFVLFRGAYQ FLVPIATFQI ASSLSKELCA LVFGINTFLA TALKTCITLV VSDKRGLGLQ 
       430        440        450        460        470        480 
VRDQFRIYFI YFLMLSITCF AWAGLDGLRY CQRGRHQPLA QAQELRSPLE TSVQAISLQD 
       490        500        510    
GDLRGPQPSA PQLLSEDGME DDRGDLRVEA KA         10         20         30         40         50         60 
MVPTGQVAEK QAYEEPRQDH ELKSWRCLVF YLCFFGFMAQ LRPGESFITP FLLERKFTKE 
        70         80         90        100        110        120 
QVTNEIIPML PYSHLAVLVP VFLLTDYLRY KPVLVLQCLS FVCVWLLLLL GTSVVHMQLM 
       130        140        150        160        170        180 
EVFYSVTMAA RIAYSSYIFS LVHPSRYQRM ASYSRAAVLL GVFISSVLGQ ALVTVGHIST 
       190        200        210        220        230        240 
YTLNCVSLGF ILFSLVLSLF LKRPKRSLFF NRSTLARGAL PCELDQMHPG PDRPETRKLD 
       250        260        270        280        290        300 
RMLGTCRDSF LVRMLSELVE NARQPQLRLW CLWWVFNSSG YYLITYYVHV LWRSTDSSLS 
       310        320        330        340        350        360 
YNGAVDAAST LLSAITSFSA GFLSIRWTLW SKLVIAGVIA IQASLVFCMF QIRDIWVCYV 
       370        380        390        400        410        420 
TFVLFRGAYQ FLVPIATFQI ASSLSKELCA LVFGINTFLA TALKTCITLV VSDKRGLGLQ 
       430        440        450        460        470        480 
VRDQFRIYFI YFLMLSITCF AWAGLDGLRY CQRGRHQPLA QAQELRSPLE TSVQAISLQD 
       490        500        510    
GDLRGPQPSA PQLLSEDGME DDRGDLRVEA KA         10         20         30         40         50         60 
MVPTGQVAEK QAYEEPRQDH ELKSWRCLVF YLCFFGFMAQ LRPGESFITP FLLERKFTKE 
        70         80         90        100        110        120 
QVTNEIIPML PYSHLAVLVP VFLLTDYLRY KPVLVLQCLS FVCVWLLLLL GTSVVHMQLM 
       130        140        150        160        170        180 
EVFYSVTMAA RIAYSSYIFS LVHPSRYQRM ASYSRAAVLL GVFISSVLGQ ALVTVGHIST 
       190        200        210        220        230        240 
YTLNCVSLGF ILFSLVLSLF LKRPKRSLFF NRSTLARGAL PCELDQMHPG PDRPETRKLD 
       250        260        270        280        290        300 
RMLGTCRDSF LVRMLSELVE NARQPQLRLW CLWWVFNSSG YYLITYYVHV LWRSTDSSLS 
       310        320        330        340        350        360 
YNGAVDAAST LLSAITSFSA GFLSIRWTLW SKLVIAGVIA IQASLVFCMF QIRDIWVCYV 
       370        380        390        400        410        420 
TFVLFRGAYQ FLVPIATFQI ASSLSKELCA LVFGINTFLA TALKTCITLV VSDKRGLGLQ 
       430        440        450        460        470        480 
VRDQFRIYFI YFLMLSITCF AWAGLDGLRY CQRGRHQPLA QAQELRSPLE TSVQAISLQD 
       490        500        510    
GDLRGPQPSA PQLLSEDGME DDRGDLRVEA KA



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P41438-1-Acetylation MVPTGQ... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P41438-1-Acetylation MVPTGQ... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt101954
    P41438-1-Acetylation MVPTGQ... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt101955
    P41438-1-unknown MVPTGQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88530
    P41438-1-unknown MVPTGQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88531

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VEAKA 512 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VEAKA 512 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt84148

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)