TopFIND 4.0

P41835: Thiamine biosynthetic bifunctional enzyme

General Information

Protein names
- Thiamine biosynthetic bifunctional enzyme
- Thiamine-phosphate synthase
- TP synthase
- TPS
- 2.5.1.3
- Thiamine-phosphate pyrophosphorylase
- TMP pyrophosphorylase
- TMP-PPase
- Hydroxyethylthiazole kinase
- 2.7.1.50
- 4-methyl-5-beta-hydroxyethylthiazole kinase
- TH kinase
- THZ kinase
Gene names THI6
Organism Saccharomyces cerevisiae
Protease Family
Protease ID
Chromosome location
UniProt ID P41835

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVFTKEEVDY SLYLVTDSTM LPPGTTLCSQ VEAGLKNGVT LVQIREKDIE TKNFVAEALE 
        70         80         90        100        110        120 
VQKICKKYNV PLIINDRIDV AMAIDADGVH VGQDDMPIPM VRKLLGPSKI LGWSVGKPSE 
       130        140        150        160        170        180 
VETLAKWGPD MVDYIGVGTL FPTSTKKNPK KSPMGPQGAI AILDALEEFK ATWCRTVGIG 
       190        200        210        220        230        240 
GLHPDNIQRV LCQCVASNGK RSLDGISLVS DIMAAPDACA ATKRLRGLLD ATRYQFVECE 
       250        260        270        280        290        300 
LNNTFPTTTS IQNVISQVSN NRPLVQHITN KVHQNFGANV TLALGSSPIM SEIESEVSEL 
       310        320        330        340        350        360 
ARIPNASLLL NTGSVAPIEM LKAAINAYNE VNRPITFDPV GYSATETRLC LNNTLLTYGQ 
       370        380        390        400        410        420 
FACIKGNCSE ILSLAKLNNH KMKGVDSSSG KTNIDTLVRA TQIVAFQYRT VAVCTGEFDC 
       430        440        450        460        470        480 
VADGTFGGEY KLSSGTEGIT AEDLPCVIIE DGPIPIMGDI TASGCSLGST IASFIGGLDS 
       490        500        510        520        530        540 
TGKLFDAVVG AVLLYKSAGK LASTRCQGSG SFHVELIDAL YQLFHENKPE KWSASLKKFK 
   

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P41835-1-unknown MVFTKE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LKKFK 540 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)