P42330: Aldo-keto reductase family 1 member C3

General Information

Protein names	- Aldo-keto reductase family 1 member C3 - 1.-.-.- - 17-beta-hydroxysteroid dehydrogenase type 5 - 17-beta-HSD 5 - 3-alpha-HSD type II, brain - 3-alpha-hydroxysteroid dehydrogenase type 2 - 3-alpha-HSD type 2 - 1.1.1.357 {ECO:0000269\|PubMed:10622721, ECO:0000269\|PubMed:11165022, ECO:0000269\|PubMed:7650035, ECO:0000269\|PubMed:9415401, ECO:0000269\|PubMed:9927279} - Chlordecone reductase homolog HAKRb - Dihydrodiol dehydrogenase 3 - DD-3 - DD3 - Dihydrodiol dehydrogenase type I - HA1753 - Indanol dehydrogenase - 1.1.1.112 - Prostaglandin F synthase - PGFS - 1.1.1.188 {ECO:0000269\|PubMed:10622721, ECO:0000269\|PubMed:11165022, ECO:0000269\|PubMed:7650035, ECO:0000269\|PubMed:9415401, ECO:0000269\|PubMed:9927279} - Testosterone 17-beta-dehydrogenase 5 - 1.1.1.239 {ECO:0000269\|PubMed:10622721, ECO:0000269\|PubMed:11165022, ECO:0000269\|PubMed:7650035, ECO:0000269\|PubMed:9415401, ECO:0000269\|PubMed:9927279} - 1.1.1.64 {ECO:0000269\|PubMed:10622721, ECO:0000269\|PubMed:11165022, ECO:0000269\|PubMed:7650035, ECO:0000269\|PubMed:9415401, ECO:0000269\|PubMed:9927279} - Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase - 1.3.1.20
Gene names	AKR1C3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P42330

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ
        70         80         90        100        110        120
VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM
       130        140        150        160        170        180
SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP
       190        200        210        220        230        240
GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD IVLVAYSALG SQRDKRWVDP NSPVLLEDPV
       250        260        270        280        290        300
LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTA EDMKAIDGLD
       310        320
RNLHYFNSDS FASHPNYPYS DEY

Isoforms

- Isoform 2 of Aldo-keto reductase family 1 member C3

Sequence View

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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P42330-1-unknown	MDSKHQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P42330-120-unknown	MSLKPG...	120		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000401327

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EMILNK	178	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000474188
...EMILNK	178	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000474373
...YSDEY	323	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)