P42338: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

General Information

Protein names	- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform - PI3-kinase subunit beta - PI3K-beta - PI3Kbeta - PtdIns-3-kinase subunit beta - 2.7.1.153 - Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta - PtdIns-3-kinase subunit p110-beta - p110beta
Gene names	PIK3CB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P42338

2 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MCFSFIMPPA MADILDIWAV DSQIASDGSI PVDFLLPTGI YIQLEVPREA TISYIKQMLW
        70         80         90        100        110        120
KQVHNYPMFN LLMDIDSYMF ACVNQTAVYE ELEDETRRLC DVRPFLPVLK LVTRSCDPGE
       130        140        150        160        170        180
KLDSKIGVLI GKGLHEFDSL KDPEVNEFRR KMRKFSEEKI LSLVGLSWMD WLKQTYPPEH
       190        200        210        220        230        240
EPSIPENLED KLYGGKLIVA VHFENCQDVF SFQVSPNMNP IKVNELAIQK RLTIHGKEDE
       250        260        270        280        290        300
VSPYDYVLQV SGRVEYVFGD HPLIQFQYIR NCVMNRALPH FILVECCKIK KMYEQEMIAI
       310        320        330        340        350        360
EAAINRNSSN LPLPLPPKKT RIISHVWENN NPFQIVLVKG NKLNTEETVK VHVRAGLFHG
       370        380        390        400        410        420
TELLCKTIVS SEVSGKNDHI WNEPLEFDIN ICDLPRMARL CFAVYAVLDK VKTKKSTKTI
       430        440        450        460        470        480
NPSKYQTIRK AGKVHYPVAW VNTMVFDFKG QLRTGDIILH SWSSFPDELE EMLNPMGTVQ
       490        500        510        520        530        540
TNPYTENATA LHVKFPENKK QPYYYPPFDK IIEKAAEIAS SDSANVSSRG GKKFLPVLKE
       550        560        570        580        590        600
ILDRDPLSQL CENEMDLIWT LRQDCREIFP QSLPKLLLSI KWNKLEDVAQ LQALLQIWPK
       610        620        630        640        650        660
LPPREALELL DFNYPDQYVR EYAVGCLRQM SDEELSQYLL QLVQVLKYEP FLDCALSRFL
       670        680        690        700        710        720
LERALGNRRI GQFLFWHLRS EVHIPAVSVQ FGVILEAYCR GSVGHMKVLS KQVEALNKLK
       730        740        750        760        770        780
TLNSLIKLNA VKLNRAKGKE AMHTCLKQSA YREALSDLQS PLNPCVILSE LYVEKCKYMD
       790        800        810        820        830        840
SKMKPLWLVY NNKVFGEDSV GVIFKNGDDL RQDMLTLQML RLMDLLWKEA GLDLRMLPYG
       850        860        870        880        890        900
CLATGDRSGL IEVVSTSETI ADIQLNSSNV AAAAAFNKDA LLNWLKEYNS GDDLDRAIEE
       910        920        930        940        950        960
FTLSCAGYCV ASYVLGIGDR HSDNIMVKKT GQLFHIDFGH ILGNFKSKFG IKRERVPFIL
       970        980        990       1000       1010       1020
TYDFIHVIQQ GKTGNTEKFG RFRQCCEDAY LILRRHGNLF ITLFALMLTA GLPELTSVKD
      1030       1040       1050       1060       1070
IQYLKDSLAL GKSEEEALKQ FKQKFDEALR ESWTTKVNWM AHTVRKDYRS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P42338-1-unknown	MCFSFI...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P42338-555-unknown	MDLIWT...	555		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000438259

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ISYIKQ	56	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417329
...TRRLCD	100	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000420399
...GVLIGK	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419857
...KTIVSS	370	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418834
...KDYRS	1070	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)