TopFIND 4.0

P42772: Cyclin-dependent kinase 4 inhibitor B

General Information

Protein names
- Cyclin-dependent kinase 4 inhibitor B
- Multiple tumor suppressor 2
- MTS-2
- p14-INK4b
- p15-INK4b
- p15INK4B
Gene names CDKN2B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P42772

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MREENKGMPS GGGSDEGLAS AAARGLVEKV RQLLEAGADP NGVNRFGRRA IQVMMMGSAR 
        70         80         90        100        110        120 
VAELLLLHGA EPNCADPATL TRPVHDAARE GFLDTLVVLH RAGARLDVRD AWGRLPVDLA 
       130    
EERGHRDVAG YLRTATGD

Isoforms

- Isoform 2 of Cyclin-dependent kinase 4 inhibitor B

Sequence View

        10         20         30         40         50         60 
MREENKGMPS GGGSDEGLAS AAARGLVEKV RQLLEAGADP NGVNRFGRRA IQVMMMGSAR 
        70         80         90        100        110        120 
VAELLLLHGA EPNCADPATL TRPVHDAARE GFLDTLVVLH RAGARLDVRD AWGRLPVDLA 
       130    
EERGHRDVAG YLRTATGD



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P42772-1-unknown MREENK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P42772-1-unknown MREENK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70139

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TATGD 138 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)