P43251: Biotinidase

General Information

Protein names	- Biotinidase - Biotinase - 3.5.1.12
Gene names	BTD
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P43251

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Biotinidase - Isoform 3 of Biotinidase - Isoform 4 of Biotinidase

Sequence View

        10         20         30         40         50         60
MAHAHIQGGR RAKSRFVVCI MSGARSKLAL FLCGCYVVAL GAHTGEESVA DHHEAEYYVA
        70         80         90        100        110        120
AVYEHPSILS LNPLALISRQ EALELMNQNL DIYEQQVMTA AQKDVQIIVF PEDGIHGFNF
       130        140        150        160        170        180
TRTSIYPFLD FMPSPQVVRW NPCLEPHRFN DTEVLQRLSC MAIRGDMFLV ANLGTKEPCH
       190        200        210        220        230        240
SSDPRCPKDG RYQFNTNVVF SNNGTLVDRY RKHNLYFEAA FDVPLKVDLI TFDTPFAGRF
       250        260        270        280        290        300
GIFTCFDILF FDPAIRVLRD YKVKHVVYPT AWMNQLPLLA AIEIQKAFAV AFGINVLAAN
       310        320        330        340        350        360
VHHPVLGMTG SGIHTPLESF WYHDMENPKS HLIIAQVAKN PVGLIGAENA TGETDPSHSK
       370        380        390        400        410        420
FLKILSGDPY CEKDAQEVHC DEATKWNVNA PPTFHSEMMY DNFTLVPVWG KEGYLHVCSN
       430        440        450        460        470        480
GLCCYLLYER PTLSKELYAL GVFDGLHTVH GTYYIQVCAL VRCGGLGFDT CGQEITEATG
       490        500        510        520        530        540
IFEFHLWGNF STSYIFPLFL TSGMTLEVPD QLGWENDHYF LRKSRLSSGL VTAALYGRLY

ERD         10         20         30         40         50         60
MAHAHIQGGR RAKSRFVVCI MSGARSKLAL FLCGCYVVAL GAHTGEESVA DHHEAEYYVA
        70         80         90        100        110        120
AVYEHPSILS LNPLALISRQ EALELMNQNL DIYEQQVMTA AQKDVQIIVF PEDGIHGFNF
       130        140        150        160        170        180
TRTSIYPFLD FMPSPQVVRW NPCLEPHRFN DTEVLQRLSC MAIRGDMFLV ANLGTKEPCH
       190        200        210        220        230        240
SSDPRCPKDG RYQFNTNVVF SNNGTLVDRY RKHNLYFEAA FDVPLKVDLI TFDTPFAGRF
       250        260        270        280        290        300
GIFTCFDILF FDPAIRVLRD YKVKHVVYPT AWMNQLPLLA AIEIQKAFAV AFGINVLAAN
       310        320        330        340        350        360
VHHPVLGMTG SGIHTPLESF WYHDMENPKS HLIIAQVAKN PVGLIGAENA TGETDPSHSK
       370        380        390        400        410        420
FLKILSGDPY CEKDAQEVHC DEATKWNVNA PPTFHSEMMY DNFTLVPVWG KEGYLHVCSN
       430        440        450        460        470        480
GLCCYLLYER PTLSKELYAL GVFDGLHTVH GTYYIQVCAL VRCGGLGFDT CGQEITEATG
       490        500        510        520        530        540
IFEFHLWGNF STSYIFPLFL TSGMTLEVPD QLGWENDHYF LRKSRLSSGL VTAALYGRLY

ERD         10         20         30         40         50         60
MAHAHIQGGR RAKSRFVVCI MSGARSKLAL FLCGCYVVAL GAHTGEESVA DHHEAEYYVA
        70         80         90        100        110        120
AVYEHPSILS LNPLALISRQ EALELMNQNL DIYEQQVMTA AQKDVQIIVF PEDGIHGFNF
       130        140        150        160        170        180
TRTSIYPFLD FMPSPQVVRW NPCLEPHRFN DTEVLQRLSC MAIRGDMFLV ANLGTKEPCH
       190        200        210        220        230        240
SSDPRCPKDG RYQFNTNVVF SNNGTLVDRY RKHNLYFEAA FDVPLKVDLI TFDTPFAGRF
       250        260        270        280        290        300
GIFTCFDILF FDPAIRVLRD YKVKHVVYPT AWMNQLPLLA AIEIQKAFAV AFGINVLAAN
       310        320        330        340        350        360
VHHPVLGMTG SGIHTPLESF WYHDMENPKS HLIIAQVAKN PVGLIGAENA TGETDPSHSK
       370        380        390        400        410        420
FLKILSGDPY CEKDAQEVHC DEATKWNVNA PPTFHSEMMY DNFTLVPVWG KEGYLHVCSN
       430        440        450        460        470        480
GLCCYLLYER PTLSKELYAL GVFDGLHTVH GTYYIQVCAL VRCGGLGFDT CGQEITEATG
       490        500        510        520        530        540
IFEFHLWGNF STSYIFPLFL TSGMTLEVPD QLGWENDHYF LRKSRLSSGL VTAALYGRLY

ERD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P43251-21-unknown	MSGARS...	21	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000397113
P43251-21-unknown	MSGARS...	21	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394277
P43251-21-unknown	MSGARS...	21	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000373288
P43251-21-unknown	MSGARS...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132404
P43251-21-unknown	MSGARS...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132405
P43251-42-unknown	AHTGEE...	42	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P43251-42-unknown	AHTGEE...	42	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt115476
P43251-42-unknown	AHTGEE...	42	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt115477

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LALISR	78	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000397113
...LALISR	78	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113849
...LALISR	78	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113850
...VYPTAW	271	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394277
...VYPTAW	271	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113852
...VYPTAW	271	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113853
...LYERD	543	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LYERD	543	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt64350
...LYERD	543	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt64351

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)