P45952: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

General Information

Protein names	- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial - MCAD - 1.3.8.7
Gene names	Acadm
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P45952

3 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAAFRRGCR VLRSVSHFEC RTQHSKAAHK QEPGLGFSFE LTEQQKEFQA TARKFAREEI
        70         80         90        100        110        120
IPVAPEYDKS GEYPFPLIKR AWELGLINAH IPESCGGLGL GTFDACLITE ELAYGCTGVQ
       130        140        150        160        170        180
TAIEANSLGQ MPVILAGNDQ QKKKYLGRMT EQPMMCAYCV TEPSAGSDVA AIKTKAEKKG
       190        200        210        220        230        240
DEYVINGQKM WITNGGKANW YFLLARSNPD PKVPASKAFT GFIVEADTPG IHIGKKELNM
       250        260        270        280        290        300
GQRCSDTRGI AFEDVRVPKE NVLIGEGAGF KIAMGAFDRT RPTVAAGAVG LAQRALDEAT
       310        320        330        340        350        360
KYALDRKTFG KLLVEHQGVS FLLAEMAMKV ELARLSYQRA AWEVDSGRRN TYYASIAKAF
       370        380        390        400        410        420
AGDIANQLAT DAVQIFGGYG FNTEYPVEKL MRDAKIYQIY EGTAQIQRLI IAREHIEKYK

N

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P45952-26-unknown	KAAHKQ...	26	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P45952-26-unknown	KAAHKQ...	26	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P45952-40-unknown	ELTEQQ...	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29958
P45952-42-unknown	TEQQKE...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29959

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LGFSFE	39	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29958
...FSFELT	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29959
...IKTKAE	176	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121714
...EKYKN	421	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	39	FSFE.\|.ELTE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACADM_MOUSE @39
CATE_MOUSE	41	FELT.\|.TEQQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ACADM_MOUSE @41

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)