P46098: 5-hydroxytryptamine receptor 3A

General Information

Protein names	- 5-hydroxytryptamine receptor 3A - 5-HT3-A - 5-HT3A - 5-hydroxytryptamine receptor 3 - 5-HT-3 - 5-HT3R - Serotonin receptor 3A - Serotonin-gated ion channel receptor
Gene names	HTR3A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P46098

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of 5-hydroxytryptamine receptor 3A - Isoform 3 of 5-hydroxytryptamine receptor 3A - Isoform 4 of 5-hydroxytryptamine receptor 3A - Isoform 5 of 5-hydroxytryptamine receptor 3A

Sequence View

        10         20         30         40         50         60
MLLWVQQALL ALLLPTLLAQ GEARRSRNTT RPALLRLSDY LLTNYRKGVR PVRDWRKPTT
        70         80         90        100        110        120
VSIDVIVYAI LNVDEKNQVL TTYIWYRQYW TDEFLQWNPE DFDNITKLSI PTDSIWVPDI
       130        140        150        160        170        180
LINEFVDVGK SPNIPYVYIR HQGEVQNYKP LQVVTACSLD IYNFPFDVQN CSLTFTSWLH
       190        200        210        220        230        240
TIQDINISLW RLPEKVKSDR SVFMNQGEWE LLGVLPYFRE FSMESSNYYA EMKFYVVIRR
       250        260        270        280        290        300
RPLFYVVSLL LPSIFLMVMD IVGFYLPPNS GERVSFKITL LLGYSVFLII VSDTLPATAI
       310        320        330        340        350        360
GTPLIGVYFV VCMALLVISL AETIFIVRLV HKQDLQQPVP AWLRHLVLER IAWLLCLREQ
       370        380        390        400        410        420
STSQRPPATS QATKTDDCSA MGNHCSHMGG PQDFEKSPRD RCSPPPPPRE ASLAVCGLLQ
       430        440        450        460        470
ELSSIRQFLE KRDEIREVAR DWLRVGSVLD KLLFHIYLLA VLAYSITLVM LWSIWQYA         10         20         30         40         50         60
MLLWVQQALL ALLLPTLLAQ GEARRSRNTT RPALLRLSDY LLTNYRKGVR PVRDWRKPTT
        70         80         90        100        110        120
VSIDVIVYAI LNVDEKNQVL TTYIWYRQYW TDEFLQWNPE DFDNITKLSI PTDSIWVPDI
       130        140        150        160        170        180
LINEFVDVGK SPNIPYVYIR HQGEVQNYKP LQVVTACSLD IYNFPFDVQN CSLTFTSWLH
       190        200        210        220        230        240
TIQDINISLW RLPEKVKSDR SVFMNQGEWE LLGVLPYFRE FSMESSNYYA EMKFYVVIRR
       250        260        270        280        290        300
RPLFYVVSLL LPSIFLMVMD IVGFYLPPNS GERVSFKITL LLGYSVFLII VSDTLPATAI
       310        320        330        340        350        360
GTPLIGVYFV VCMALLVISL AETIFIVRLV HKQDLQQPVP AWLRHLVLER IAWLLCLREQ
       370        380        390        400        410        420
STSQRPPATS QATKTDDCSA MGNHCSHMGG PQDFEKSPRD RCSPPPPPRE ASLAVCGLLQ
       430        440        450        460        470
ELSSIRQFLE KRDEIREVAR DWLRVGSVLD KLLFHIYLLA VLAYSITLVM LWSIWQYA         10         20         30         40         50         60
MLLWVQQALL ALLLPTLLAQ GEARRSRNTT RPALLRLSDY LLTNYRKGVR PVRDWRKPTT
        70         80         90        100        110        120
VSIDVIVYAI LNVDEKNQVL TTYIWYRQYW TDEFLQWNPE DFDNITKLSI PTDSIWVPDI
       130        140        150        160        170        180
LINEFVDVGK SPNIPYVYIR HQGEVQNYKP LQVVTACSLD IYNFPFDVQN CSLTFTSWLH
       190        200        210        220        230        240
TIQDINISLW RLPEKVKSDR SVFMNQGEWE LLGVLPYFRE FSMESSNYYA EMKFYVVIRR
       250        260        270        280        290        300
RPLFYVVSLL LPSIFLMVMD IVGFYLPPNS GERVSFKITL LLGYSVFLII VSDTLPATAI
       310        320        330        340        350        360
GTPLIGVYFV VCMALLVISL AETIFIVRLV HKQDLQQPVP AWLRHLVLER IAWLLCLREQ
       370        380        390        400        410        420
STSQRPPATS QATKTDDCSA MGNHCSHMGG PQDFEKSPRD RCSPPPPPRE ASLAVCGLLQ
       430        440        450        460        470
ELSSIRQFLE KRDEIREVAR DWLRVGSVLD KLLFHIYLLA VLAYSITLVM LWSIWQYA         10         20         30         40         50         60
MLLWVQQALL ALLLPTLLAQ GEARRSRNTT RPALLRLSDY LLTNYRKGVR PVRDWRKPTT
        70         80         90        100        110        120
VSIDVIVYAI LNVDEKNQVL TTYIWYRQYW TDEFLQWNPE DFDNITKLSI PTDSIWVPDI
       130        140        150        160        170        180
LINEFVDVGK SPNIPYVYIR HQGEVQNYKP LQVVTACSLD IYNFPFDVQN CSLTFTSWLH
       190        200        210        220        230        240
TIQDINISLW RLPEKVKSDR SVFMNQGEWE LLGVLPYFRE FSMESSNYYA EMKFYVVIRR
       250        260        270        280        290        300
RPLFYVVSLL LPSIFLMVMD IVGFYLPPNS GERVSFKITL LLGYSVFLII VSDTLPATAI
       310        320        330        340        350        360
GTPLIGVYFV VCMALLVISL AETIFIVRLV HKQDLQQPVP AWLRHLVLER IAWLLCLREQ
       370        380        390        400        410        420
STSQRPPATS QATKTDDCSA MGNHCSHMGG PQDFEKSPRD RCSPPPPPRE ASLAVCGLLQ
       430        440        450        460        470
ELSSIRQFLE KRDEIREVAR DWLRVGSVLD KLLFHIYLLA VLAYSITLVM LWSIWQYA

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P46098-1-unknown	MLLWVQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65791
P46098-1-unknown	MLLWVQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109955
P46098-1-unknown	MLLWVQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109956
P46098-24-unknown	RRSRNT...	24	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P46098-24-unknown	RRSRNT...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113528
P46098-24-unknown	RRSRNT...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113529
P46098-24-unknown	RRSRNT...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113526
P46098-24-unknown	RRSRNT...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113527

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IWQYA	478	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...IWQYA	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61410
...IWQYA	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61411
...IWQYA	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61409
...IWQYA	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61412

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

P46098: 5-hydroxytryptamine receptor 3A

General Information

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates