P46935: E3 ubiquitin-protein ligase NEDD4
| Protein names | - E3 ubiquitin-protein ligase NEDD4 - 2.3.2.26 {ECO:0000250|UniProtKB:P46934} - HECT-type E3 ubiquitin transferase NEDD4 - Neural precursor cell expressed developmentally down-regulated protein 4 - NEDD-4 |
|---|---|
| Gene names | Nedd4 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P46935 |
5
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSSDMAADES EAPVLSEDEV WEFCLDKTED GGGSPGSDVT DTCEPPCGCW ELNPNSLEEE
70 80 90 100 110 120
HVLFTADPYL ELHNDDTRVV RVKVIAGIGL AKKDILGASD PYVRVTLYDP MSGILTSVQT
130 140 150 160 170 180
KTIKKSLNPK WNEEILFRVL PQRHRILFEV FDENRLTRDD FLGQVDVPLY PLPTENPRME
190 200 210 220 230 240
RPYTFKDFVL HPRSHKSRVK GYLRLKMTYL PKNGSEDENA DQAEELEPGW VVLDQPDAAT
250 260 270 280 290 300
HLPHPPEPSP LPPGWEERQD VLGRTYYVNH ESRRTQWKRP SPDDDLTDED NDDMQLQAQR
310 320 330 340 350 360
AFTTRRQISE DVDGPDNRES PENWEIVRED ENTEYSGQAV QSPPSGHIDV QTHLAEEFNT
370 380 390 400 410 420
RLAVCGNPAT SQPVTSSNHS SRGGSLQTCI FEEQPTLPVL LPTSSGLPPG WEEKQDDRGR
430 440 450 460 470 480
SYYVDHNSKT TTWSKPTMQD DPRSKIPAHL RGKTDSNDLG PLPPGWEERT HTDGRVFFIN
490 500 510 520 530 540
HNIKKTQWED PRLQNVAITG PAVPYSRDYK RKYEFFRRKL KKQTDIPNKF EMKLRRANIL
550 560 570 580 590 600
EDSYRRIMGV KRADLLKARL WIEFDGEKGL DYGGVAREWF FLISKEMFNP YYGLFEYSAT
610 620 630 640 650 660
DNYTLQINPN SGLCNEDHLS YFKFIGRVAG MAVYHGKLLD GFFIRPFYKM MLQKLITLHD
670 680 690 700 710 720
MESVDSEYYS SLRWILENDP TELDLRFIID EELFGQTHQH ELKTGGSEIV VTNKNKKEYI
730 740 750 760 770 780
YLVIQWRFVN RIQKQMAAFK EGFFELIPQD LIKIFDENEL ELLMCGLGDV DVNDWREHTK
790 800 810 820 830 840
YKNGYSMNHQ VIHWFWKAVW MMDSEKRIRL LQFVTGTSRV PMNGFAELYG SNGPQSFTVE
850 860 870 880
QWGTPDKLPR AHTCFNRLDL PPYESFDELW DKLQMAIENT QGFDGVD
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
5 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P46935-1-unknown | MSSDMA... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P46935-5-unknown | MAADES... | 5 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| P46935-20-unknown | VWEFCL... | 20 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| P46935-46-unknown | PCGCWE... | 46 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| P46935-111-unknown | MSGILT... | 111 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000139190 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LPKNGS | 214 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000138852 | |||
| ...FDGVD | 887 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|