TopFIND 4.0

P46952: 3-hydroxyanthranilate 3,4-dioxygenase {ECO:0000255|HAMAP-Rule:MF_03019}

General Information

Protein names
- 3-hydroxyanthranilate 3,4-dioxygenase {ECO:0000255|HAMAP-Rule:MF_03019}
- 1.13.11.6 {ECO:0000255|HAMAP-Rule:MF_03019, ECO:0000269|PubMed:7514594}
- 3-hydroxyanthranilate oxygenase {ECO:0000255|HAMAP-Rule:MF_03019}
- 3-HAO {ECO:0000255|HAMAP-Rule:MF_03019}
- h3HAO {ECO:0000303|PubMed:28375145}
- 3-hydroxyanthranilic acid dioxygenase {ECO:0000255|HAMAP-Rule:MF_03019}
- HAD {ECO:0000255|HAMAP-Rule:MF_03019}
Gene names HAAO
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P46952

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MERRLGVRAW VKENRGSFQP PVCNKLMHQE QLKVMFIGGP NTRKDYHIEE GEEVFYQLEG 
        70         80         90        100        110        120 
DMVLRVLEQG KHRDVVIRQG EIFLLPARVP HSPQRFANTV GLVVERRRLE TELDGLRYYV 
       130        140        150        160        170        180 
GDTMDVLFEK WFYCKDLGTQ LAPIIQEFFS SEQYRTGKPI PDQLLKEPPF PLSTRSIMEP 
       190        200        210        220        230        240 
MSLDAWLDSH HRELQAGTPL SLFGDTYETQ VIAYGQGSSE GLRQNVDVWL WQLEGSSVVT 
       250        260        270        280    
MGGRRLSLAP DDSLLVLAGT SYAWERTQGS VALSVTQDPA CKKPLG

Isoforms

- Isoform 2 of 3-hydroxyanthranilate 3,4-dioxygenase

Sequence View

        10         20         30         40         50         60 
MERRLGVRAW VKENRGSFQP PVCNKLMHQE QLKVMFIGGP NTRKDYHIEE GEEVFYQLEG 
        70         80         90        100        110        120 
DMVLRVLEQG KHRDVVIRQG EIFLLPARVP HSPQRFANTV GLVVERRRLE TELDGLRYYV 
       130        140        150        160        170        180 
GDTMDVLFEK WFYCKDLGTQ LAPIIQEFFS SEQYRTGKPI PDQLLKEPPF PLSTRSIMEP 
       190        200        210        220        230        240 
MSLDAWLDSH HRELQAGTPL SLFGDTYETQ VIAYGQGSSE GLRQNVDVWL WQLEGSSVVT 
       250        260        270        280    
MGGRRLSLAP DDSLLVLAGT SYAWERTQGS VALSVTQDPA CKKPLG



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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P46952-1-unknown MERRLG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P46952-1-unknown MERRLG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65769

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PIIQEF 147 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61387
    ...KKPLG 286 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)