P47736: Rap1 GTPase-activating protein 1

General Information

Protein names	- Rap1 GTPase-activating protein 1 - Rap1GAP - Rap1GAP1
Gene names	RAP1GAP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P47736

1 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Rap1 GTPase-activating protein 1 - Isoform 3 of Rap1 GTPase-activating protein 1 - Isoform 4 of Rap1 GTPase-activating protein 1

Sequence View

        10         20         30         40         50         60
MIEKMQGSRM DEQRCSFPPP LKTEEDYIPY PSVHEVLGRE GPFPLILLPQ FGGYWIEGTN
        70         80         90        100        110        120
HEITSIPETE PLQSPTTKVK LECNPTARIY RKHFLGKEHF NYYSLDAALG HLVFSLKYDV
       130        140        150        160        170        180
IGDQEHLRLL LRTKCRTYHD VIPISCLTEF PNVVQMAKLV CEDVNVDRFY PVLYPKASRL
       190        200        210        220        230        240
IVTFDEHVIS NNFKFGVIYQ KLGQTSEEEL FSTNEESPAF VEFLEFLGQK VKLQDFKGFR
       250        260        270        280        290        300
GGLDVTHGQT GTESVYCNFR NKEIMFHVST KLPYTEGDAQ QLQRKRHIGN DIVAVVFQDE
       310        320        330        340        350        360
NTPFVPDMIA SNFLHAYVVV QAEGGGPDGP LYKVSVTARD DVPFFGPPLP DPAVFRKGPE
       370        380        390        400        410        420
FQEFLLTKLI NAEYACYKAE KFAKLEERTR AALLETLYEE LHIHSQSMMG LGGDEDKMEN
       430        440        450        460        470        480
GSGGGGFFES FKRVIRSRSQ SMDAMGLSNK KPNTVSTSHS GSFAPNNPDL AKAAGISLIV
       490        500        510        520        530        540
PGKSPTRKKS GPFGSRRSSA IGIENIQEVQ EKRESPPAGQ KTPDSGHVSQ EPKSENSSTQ
       550        560        570        580        590        600
SSPEMPTTKN RAETAAQRAE ALKDFSRSSS SASSFASVVE ETEGVDGEDT GLESVSSSGT
       610        620        630        640        650        660
PHKRDSFIYS TWLEDSVSTT SGGSSPGPSR SPHPDAGKLG DPACPEIKIQ LEASEQHMPQ

LGC         10         20         30         40         50         60
MIEKMQGSRM DEQRCSFPPP LKTEEDYIPY PSVHEVLGRE GPFPLILLPQ FGGYWIEGTN
        70         80         90        100        110        120
HEITSIPETE PLQSPTTKVK LECNPTARIY RKHFLGKEHF NYYSLDAALG HLVFSLKYDV
       130        140        150        160        170        180
IGDQEHLRLL LRTKCRTYHD VIPISCLTEF PNVVQMAKLV CEDVNVDRFY PVLYPKASRL
       190        200        210        220        230        240
IVTFDEHVIS NNFKFGVIYQ KLGQTSEEEL FSTNEESPAF VEFLEFLGQK VKLQDFKGFR
       250        260        270        280        290        300
GGLDVTHGQT GTESVYCNFR NKEIMFHVST KLPYTEGDAQ QLQRKRHIGN DIVAVVFQDE
       310        320        330        340        350        360
NTPFVPDMIA SNFLHAYVVV QAEGGGPDGP LYKVSVTARD DVPFFGPPLP DPAVFRKGPE
       370        380        390        400        410        420
FQEFLLTKLI NAEYACYKAE KFAKLEERTR AALLETLYEE LHIHSQSMMG LGGDEDKMEN
       430        440        450        460        470        480
GSGGGGFFES FKRVIRSRSQ SMDAMGLSNK KPNTVSTSHS GSFAPNNPDL AKAAGISLIV
       490        500        510        520        530        540
PGKSPTRKKS GPFGSRRSSA IGIENIQEVQ EKRESPPAGQ KTPDSGHVSQ EPKSENSSTQ
       550        560        570        580        590        600
SSPEMPTTKN RAETAAQRAE ALKDFSRSSS SASSFASVVE ETEGVDGEDT GLESVSSSGT
       610        620        630        640        650        660
PHKRDSFIYS TWLEDSVSTT SGGSSPGPSR SPHPDAGKLG DPACPEIKIQ LEASEQHMPQ

LGC         10         20         30         40         50         60
MIEKMQGSRM DEQRCSFPPP LKTEEDYIPY PSVHEVLGRE GPFPLILLPQ FGGYWIEGTN
        70         80         90        100        110        120
HEITSIPETE PLQSPTTKVK LECNPTARIY RKHFLGKEHF NYYSLDAALG HLVFSLKYDV
       130        140        150        160        170        180
IGDQEHLRLL LRTKCRTYHD VIPISCLTEF PNVVQMAKLV CEDVNVDRFY PVLYPKASRL
       190        200        210        220        230        240
IVTFDEHVIS NNFKFGVIYQ KLGQTSEEEL FSTNEESPAF VEFLEFLGQK VKLQDFKGFR
       250        260        270        280        290        300
GGLDVTHGQT GTESVYCNFR NKEIMFHVST KLPYTEGDAQ QLQRKRHIGN DIVAVVFQDE
       310        320        330        340        350        360
NTPFVPDMIA SNFLHAYVVV QAEGGGPDGP LYKVSVTARD DVPFFGPPLP DPAVFRKGPE
       370        380        390        400        410        420
FQEFLLTKLI NAEYACYKAE KFAKLEERTR AALLETLYEE LHIHSQSMMG LGGDEDKMEN
       430        440        450        460        470        480
GSGGGGFFES FKRVIRSRSQ SMDAMGLSNK KPNTVSTSHS GSFAPNNPDL AKAAGISLIV
       490        500        510        520        530        540
PGKSPTRKKS GPFGSRRSSA IGIENIQEVQ EKRESPPAGQ KTPDSGHVSQ EPKSENSSTQ
       550        560        570        580        590        600
SSPEMPTTKN RAETAAQRAE ALKDFSRSSS SASSFASVVE ETEGVDGEDT GLESVSSSGT
       610        620        630        640        650        660
PHKRDSFIYS TWLEDSVSTT SGGSSPGPSR SPHPDAGKLG DPACPEIKIQ LEASEQHMPQ

LGC

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P47736-1-unknown	MIEKMQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P47736-1-unknown	MIEKMQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt88156
P47736-1-unknown	MIEKMQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100714
P47736-1-unknown	MIEKMQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100713

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PSVHEV	35	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000392717
...PSVHEV	35	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153774
...PSVHEV	35	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153773
...PSVHEV	35	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153772
...KHFLGK	96	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000315420
...KHFLGK	96	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154318
...KHFLGK	96	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154317
...KHFLGK	96	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154316
...GKEHFN	100	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000470945
...GKEHFN	100	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154385
...GKEHFN	100	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154384
...GKEHFN	100	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154383
...QKLGQT	204	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000352739
...QKLGQT	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155674
...QKLGQT	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155673
...QKLGQT	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155672
...PQLGC	663	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PQLGC	663	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83774
...PQLGC	663	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83775
...PQLGC	663	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83776

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)