P47809: Dual specificity mitogen-activated protein kinase kinase 4

General Information

Protein names	- Dual specificity mitogen-activated protein kinase kinase 4 - MAP kinase kinase 4 - MAPKK 4 - 2.7.12.2 - C-JUN N-terminal kinase kinase 1 - JNK kinase 1 - JNKK 1 - JNK-activating kinase 1 - MAPK/ERK kinase 4 - MEK 4 - SAPK/ERK kinase 1 - SEK1
Gene names	Map2k4
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P47809

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAPSPSGGG GSGGGGGTPG PIGPPASGHP AVSSMQGKRK ALKLNFANPP VKSTARFTLN
        70         80         90        100        110        120
PNTTGVQNPH IERLRTHSIE SSGKLKISPE QHWDFTAEDL KDLGEIGRGA YGSVNKMVHK
       130        140        150        160        170        180
PSGQIMAVKR IRSTVDEKEQ KQLLMDLDVV MRSSDCPYIV QFYGALFREG DCWICMELMS
       190        200        210        220        230        240
TSFDKFYKYV YSVLDDVIPE EILGKITLAT VKALNHLKEN LKIIHRDIKP SNILLDRSGN
       250        260        270        280        290        300
IKLCDFGISG QLVDSIAKTR DAGCRPYMAP ERIDPSASRQ GYDVRSDVWS LGITLYELAT
       310        320        330        340        350        360
GRFPYPKWNS VFDQLTQVVK GDPPQLSNSE EREFSPSFIN FVNLCLTKDE SKRPKYKELL
       370        380        390
KHPFILMYEE RTVEVACYVC KILDQMPATP SSPMYVD

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P47809-2-unknown	MAAPSP...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P47809-2-unknown	MAAPSP...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P47809-2-Acetylation	AAPSPS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P47809-2-Acetylation	AAPSPS...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P47809-130-unknown	RIRSTV...	130		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000137656

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...YSVLDD	195	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000114219
	...PMYVD	397	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)