P47811: Mitogen-activated protein kinase 14

General Information

Protein names	- Mitogen-activated protein kinase 14 - MAP kinase 14 - MAPK 14 - 2.7.11.24 {ECO:0000269\|PubMed:18669639, ECO:0000269\|PubMed:22375048} - CRK1 - Mitogen-activated protein kinase p38 alpha - MAP kinase p38 alpha
Gene names	Mapk14
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P47811

5 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Mitogen-activated protein kinase 14 - Isoform 3 of Mitogen-activated protein kinase 14 - Isoform 4 of Mitogen-activated protein kinase 14 - Isoform 2 of Mitogen-activated protein kinase 14 - Isoform 4 of Mitogen-activated protein kinase 14

Sequence View

        10         20         30         40         50         60
MSQERPTFYR QELNKTIWEV PERYQNLSPV GSGAYGSVCA AFDTKTGHRV AVKKLSRPFQ
        70         80         90        100        110        120
SIIHAKRTYR ELRLLKHMKH ENVIGLLDVF TPARSLEEFN DVYLVTHLMG ADLNNIVKCQ
       130        140        150        160        170        180
KLTDDHVQFL IYQILRGLKY IHSADIIHRD LKPSNLAVNE DCELKILDFG LARHTDDEMT
       190        200        210        220        230        240
GYVATRWYRA PEIMLNWMHY NQTVDIWSVG CIMAELLTGR TLFPGTDHID QLKLILRLVG
       250        260        270        280        290        300
TPGAELLKKI SSESARNYIQ SLAQMPKMNF ANVFIGANPL AVDLLEKMLV LDSDKRITAA
       310        320        330        340        350        360
QALAHAYFAQ YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES

        10         20         30         40         50         60
MSQERPTFYR QELNKTIWEV PERYQNLSPV GSGAYGSVCA AFDTKTGHRV AVKKLSRPFQ
        70         80         90        100        110        120
SIIHAKRTYR ELRLLKHMKH ENVIGLLDVF TPARSLEEFN DVYLVTHLMG ADLNNIVKCQ
       130        140        150        160        170        180
KLTDDHVQFL IYQILRGLKY IHSADIIHRD LKPSNLAVNE DCELKILDFG LARHTDDEMT
       190        200        210        220        230        240
GYVATRWYRA PEIMLNWMHY NQTVDIWSVG CIMAELLTGR TLFPGTDHID QLKLILRLVG
       250        260        270        280        290        300
TPGAELLKKI SSESARNYIQ SLAQMPKMNF ANVFIGANPL AVDLLEKMLV LDSDKRITAA
       310        320        330        340        350        360
QALAHAYFAQ YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES

        10         20         30         40         50         60
MSQERPTFYR QELNKTIWEV PERYQNLSPV GSGAYGSVCA AFDTKTGHRV AVKKLSRPFQ
        70         80         90        100        110        120
SIIHAKRTYR ELRLLKHMKH ENVIGLLDVF TPARSLEEFN DVYLVTHLMG ADLNNIVKCQ
       130        140        150        160        170        180
KLTDDHVQFL IYQILRGLKY IHSADIIHRD LKPSNLAVNE DCELKILDFG LARHTDDEMT
       190        200        210        220        230        240
GYVATRWYRA PEIMLNWMHY NQTVDIWSVG CIMAELLTGR TLFPGTDHID QLKLILRLVG
       250        260        270        280        290        300
TPGAELLKKI SSESARNYIQ SLAQMPKMNF ANVFIGANPL AVDLLEKMLV LDSDKRITAA
       310        320        330        340        350        360
QALAHAYFAQ YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES

        10         20         30         40         50         60
MSQERPTFYR QELNKTIWEV PERYQNLSPV GSGAYGSVCA AFDTKTGHRV AVKKLSRPFQ
        70         80         90        100        110        120
SIIHAKRTYR ELRLLKHMKH ENVIGLLDVF TPARSLEEFN DVYLVTHLMG ADLNNIVKCQ
       130        140        150        160        170        180
KLTDDHVQFL IYQILRGLKY IHSADIIHRD LKPSNLAVNE DCELKILDFG LARHTDDEMT
       190        200        210        220        230        240
GYVATRWYRA PEIMLNWMHY NQTVDIWSVG CIMAELLTGR TLFPGTDHID QLKLILRLVG
       250        260        270        280        290        300
TPGAELLKKI SSESARNYIQ SLAQMPKMNF ANVFIGANPL AVDLLEKMLV LDSDKRITAA
       310        320        330        340        350        360
QALAHAYFAQ YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES

        10         20         30         40         50         60
MSQERPTFYR QELNKTIWEV PERYQNLSPV GSGAYGSVCA AFDTKTGHRV AVKKLSRPFQ
        70         80         90        100        110        120
SIIHAKRTYR ELRLLKHMKH ENVIGLLDVF TPARSLEEFN DVYLVTHLMG ADLNNIVKCQ
       130        140        150        160        170        180
KLTDDHVQFL IYQILRGLKY IHSADIIHRD LKPSNLAVNE DCELKILDFG LARHTDDEMT
       190        200        210        220        230        240
GYVATRWYRA PEIMLNWMHY NQTVDIWSVG CIMAELLTGR TLFPGTDHID QLKLILRLVG
       250        260        270        280        290        300
TPGAELLKKI SSESARNYIQ SLAQMPKMNF ANVFIGANPL AVDLLEKMLV LDSDKRITAA
       310        320        330        340        350        360
QALAHAYFAQ YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P47811-2-unknown	MSQERP...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P47811-2-unknown	MSQERP...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P47811-1-unknown	MSQERP...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81218
P47811-1-unknown	MSQERP...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81219
P47811-2-Acetylation	SQERPT...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P47811-2-Acetylation	SQERPT...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111085
P47811-2-Acetylation	SQERPT...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111086
P47811-2-Acetylation	SQERPT...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P47811-78-unknown	MKHENV...	78		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000110402
P47811-78-unknown	MKHENV...	78		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000110400
P47811-78-unknown	MKHENV...	78		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196603
P47811-78-unknown	MKHENV...	78		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196604
P47811-78-unknown	MKHENV...	78		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196605
P47811-120-unknown	QKLTDD...	120		inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P47811-120-unknown	QKLTDD...	120		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197241
P47811-120-unknown	QKLTDD...	120		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197242
P47811-120-unknown	QKLTDD...	120		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197243

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HYNQTV	203	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116914
...HYNQTV	203	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155662
...HYNQTV	203	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155663
...HYNQTV	203	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155664
...EEMES	360	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EEMES	360	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76838
...EEMES	360	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76837

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)