P48029: Sodium- and chloride-dependent creatine transporter 1

General Information

Protein names	- Sodium- and chloride-dependent creatine transporter 1 - CT1 - Creatine transporter 1 - Solute carrier family 6 member 8
Gene names	SLC6A8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P48029

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAKKSAENGI YSVSGDEKKG PLIAPGPDGA PAKGDGPVGL GTPGGRLAVP PRETWTRQMD
        70         80         90        100        110        120
FIMSCVGFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS
       130        140        150        160        170        180
INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD
       190        200        210        220        230        240
CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSGGLEVPGA LNWEVTLCLL
       250        260        270        280        290        300
ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLVVLLVRGV LLPGALDGII YYLKPDWSKL
       310        320        330        340        350        360
GSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYKD AIILALINSG TSFFAGFVVF
       370        380        390        400        410        420
SILGFMAAEQ GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV
       430        440        450        460        470        480
GVEGFITGLL DLLPASYYFR FQREISVALC CALCFVIDLS MVTDGGMYVF QLFDYYSASG
       490        500        510        520        530        540
TTLLWQAFWE CVVVAWVYGA DRFMDDIACM IGYRPCPWMK WCWSFFTPLV CMGIFIFNVV
       550        560        570        580        590        600
YYEPLVYNNT YVYPWWGEAM GWAFALSSML CVPLHLLGCL LRAKGTMAER WQHLTQPIWG
       610        620        630
LHHLEYRAQD ADVRGLTTLT PVSESSKVVV VESVM

Isoforms

- Isoform 2 of Sodium- and chloride-dependent creatine transporter 1 - Isoform 3 of Sodium- and chloride-dependent creatine transporter 1 - Isoform 4 of Sodium- and chloride-dependent creatine transporter 1

Sequence View

        10         20         30         40         50         60
MAKKSAENGI YSVSGDEKKG PLIAPGPDGA PAKGDGPVGL GTPGGRLAVP PRETWTRQMD
        70         80         90        100        110        120
FIMSCVGFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS
       130        140        150        160        170        180
INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD
       190        200        210        220        230        240
CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSGGLEVPGA LNWEVTLCLL
       250        260        270        280        290        300
ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLVVLLVRGV LLPGALDGII YYLKPDWSKL
       310        320        330        340        350        360
GSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYKD AIILALINSG TSFFAGFVVF
       370        380        390        400        410        420
SILGFMAAEQ GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV
       430        440        450        460        470        480
GVEGFITGLL DLLPASYYFR FQREISVALC CALCFVIDLS MVTDGGMYVF QLFDYYSASG
       490        500        510        520        530        540
TTLLWQAFWE CVVVAWVYGA DRFMDDIACM IGYRPCPWMK WCWSFFTPLV CMGIFIFNVV
       550        560        570        580        590        600
YYEPLVYNNT YVYPWWGEAM GWAFALSSML CVPLHLLGCL LRAKGTMAER WQHLTQPIWG
       610        620        630
LHHLEYRAQD ADVRGLTTLT PVSESSKVVV VESVM         10         20         30         40         50         60
MAKKSAENGI YSVSGDEKKG PLIAPGPDGA PAKGDGPVGL GTPGGRLAVP PRETWTRQMD
        70         80         90        100        110        120
FIMSCVGFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS
       130        140        150        160        170        180
INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD
       190        200        210        220        230        240
CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSGGLEVPGA LNWEVTLCLL
       250        260        270        280        290        300
ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLVVLLVRGV LLPGALDGII YYLKPDWSKL
       310        320        330        340        350        360
GSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYKD AIILALINSG TSFFAGFVVF
       370        380        390        400        410        420
SILGFMAAEQ GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV
       430        440        450        460        470        480
GVEGFITGLL DLLPASYYFR FQREISVALC CALCFVIDLS MVTDGGMYVF QLFDYYSASG
       490        500        510        520        530        540
TTLLWQAFWE CVVVAWVYGA DRFMDDIACM IGYRPCPWMK WCWSFFTPLV CMGIFIFNVV
       550        560        570        580        590        600
YYEPLVYNNT YVYPWWGEAM GWAFALSSML CVPLHLLGCL LRAKGTMAER WQHLTQPIWG
       610        620        630
LHHLEYRAQD ADVRGLTTLT PVSESSKVVV VESVM         10         20         30         40         50         60
MAKKSAENGI YSVSGDEKKG PLIAPGPDGA PAKGDGPVGL GTPGGRLAVP PRETWTRQMD
        70         80         90        100        110        120
FIMSCVGFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS
       130        140        150        160        170        180
INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD
       190        200        210        220        230        240
CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSGGLEVPGA LNWEVTLCLL
       250        260        270        280        290        300
ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLVVLLVRGV LLPGALDGII YYLKPDWSKL
       310        320        330        340        350        360
GSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYKD AIILALINSG TSFFAGFVVF
       370        380        390        400        410        420
SILGFMAAEQ GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV
       430        440        450        460        470        480
GVEGFITGLL DLLPASYYFR FQREISVALC CALCFVIDLS MVTDGGMYVF QLFDYYSASG
       490        500        510        520        530        540
TTLLWQAFWE CVVVAWVYGA DRFMDDIACM IGYRPCPWMK WCWSFFTPLV CMGIFIFNVV
       550        560        570        580        590        600
YYEPLVYNNT YVYPWWGEAM GWAFALSSML CVPLHLLGCL LRAKGTMAER WQHLTQPIWG
       610        620        630
LHHLEYRAQD ADVRGLTTLT PVSESSKVVV VESVM

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P48029-1-unknown	MAKKSA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P48029-107-unknown	FLEISL...	107	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P48029-116-unknown	MKAGSI...	116	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt88962
P48029-366-unknown	MAAEQG...	366	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt88961
P48029-366-unknown	MAAEQG...	366	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt103215
P48029-366-unknown	MAAEQG...	366	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt103216

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VESVM	635	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VESVM	635	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84579
...VESVM	635	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84580
...VESVM	635	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84578

TopFIND

P48029: Sodium- and chloride-dependent creatine transporter 1

General Information

4

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates