P48048: ATP-sensitive inward rectifier potassium channel 1

General Information

Protein names	- ATP-sensitive inward rectifier potassium channel 1 - ATP-regulated potassium channel ROM-K - Inward rectifier K(+) channel Kir1.1 - Potassium channel, inwardly rectifying subfamily J member 1
Gene names	KCNJ1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P48048

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of ATP-sensitive inward rectifier potassium channel 1 - Isoform 3 of ATP-sensitive inward rectifier potassium channel 1

Sequence View

        10         20         30         40         50         60
MNASSRNVFD TLIRVLTESM FKHLRKWVVT RFFGHSRQRA RLVSKDGRCN IEFGNVEAQS
        70         80         90        100        110        120
RFIFFVDIWT TVLDLKWRYK MTIFITAFLG SWFFFGLLWY AVAYIHKDLP EFHPSANHTP
       130        140        150        160        170        180
CVENINGLTS AFLFSLETQV TIGYGFRCVT EQCATAIFLL IFQSILGVII NSFMCGAILA
       190        200        210        220        230        240
KISRPKKRAK TITFSKNAVI SKRGGKLCLL IRVANLRKSL LIGSHIYGKL LKTTVTPEGE
       250        260        270        280        290        300
TIILDQININ FVVDAGNENL FFISPLTIYH VIDHNSPFFH MAAETLLQQD FELVVFLDGT
       310        320        330        340        350        360
VESTSATCQV RTSYVPEEVL WGYRFAPIVS KTKEGKYRVD FHNFSKTVEV ETPHCAMCLY
       370        380        390
NEKDVRARMK RGYDNPNFIL SEVNETDDTK M         10         20         30         40         50         60
MNASSRNVFD TLIRVLTESM FKHLRKWVVT RFFGHSRQRA RLVSKDGRCN IEFGNVEAQS
        70         80         90        100        110        120
RFIFFVDIWT TVLDLKWRYK MTIFITAFLG SWFFFGLLWY AVAYIHKDLP EFHPSANHTP
       130        140        150        160        170        180
CVENINGLTS AFLFSLETQV TIGYGFRCVT EQCATAIFLL IFQSILGVII NSFMCGAILA
       190        200        210        220        230        240
KISRPKKRAK TITFSKNAVI SKRGGKLCLL IRVANLRKSL LIGSHIYGKL LKTTVTPEGE
       250        260        270        280        290        300
TIILDQININ FVVDAGNENL FFISPLTIYH VIDHNSPFFH MAAETLLQQD FELVVFLDGT
       310        320        330        340        350        360
VESTSATCQV RTSYVPEEVL WGYRFAPIVS KTKEGKYRVD FHNFSKTVEV ETPHCAMCLY
       370        380        390
NEKDVRARMK RGYDNPNFIL SEVNETDDTK M

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P48048-1-unknown	MNASSR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P48048-20-unknown	MFKHLR...	20	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78765
P48048-20-unknown	MFKHLR...	20	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000376433
P48048-20-unknown	MFKHLR...	20	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406320
P48048-20-unknown	MFKHLR...	20	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000316233
P48048-20-unknown	MFKHLR...	20	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000316136
P48048-20-unknown	MFKHLR...	20	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000376434
P48048-20-unknown	MFKHLR...	20	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105534

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ATAIFL	158	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000316136
...ATAIFL	158	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt111892
...ATAIFL	158	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt111893
...DDTKM	391	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DDTKM	391	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74383
...DDTKM	391	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74384

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)