TopFIND 4.0

P48065: Sodium- and chloride-dependent betaine transporter

General Information

Protein names
- Sodium- and chloride-dependent betaine transporter
- BGT-1
- Na(+)/Cl(-) betaine/GABA transporter
- Solute carrier family 6 member 12
Gene names SLC6A12
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P48065

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDGKVAVQEC GPPAVSWVPE EGEKLDQEDE DQVKDRGQWT NKMEFVLSVA GEIIGLGNVW 
        70         80         90        100        110        120 
RFPYLCYKNG GGAFFIPYFI FFFVCGIPVF FLEVALGQYT SQGSVTAWRK ICPLFQGIGL 
       130        140        150        160        170        180 
ASVVIESYLN VYYIIILAWA LFYLFSSFTS ELPWTTCNNF WNTEHCTDFL NHSGAGTVTP 
       190        200        210        220        230        240 
FENFTSPVME FWERRVLGIT SGIHDLGSLR WELALCLLLA WVICYFCIWK GVKSTGKVVY 
       250        260        270        280        290        300 
FTATFPYLML VILLIRGVTL PGAYQGIIYY LKPDLFRLKD PQVWMDAGTQ IFFSFAICQG 
       310        320        330        340        350        360 
CLTALGSYNK YHNNCYKDCI ALCFLNSATS FVAGFVVFSI LGFMSQEQGV PISEVAESGP 
       370        380        390        400        410        420 
GLAFIAFPKA VTMMPLSQLW SCLFFIMLIF LGLDSQFVCV ECLVTASIDM FPRQLRKSGR 
       430        440        450        460        470        480 
RELLILTIAV MCYLIGLFLV TEGGMYIFQL FDYYASSGIC LLFLSLFEVV CISWVYGADR 
       490        500        510        520        530        540 
FYDNIEDMIG YRPWPLVKIS WLFLTPGLCL ATFLFSLSKY TPLKYNNVYV YPPWGYSIGW 
       550        560        570        580        590        600 
FLALSSMVCV PLFVVITLLK TRGPFRKRLR QLITPDSSLP QPKQHPCLDG SAGRNFGPSP 
       610    
TREGLIAGEK ETHL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P48065-1-unknown MDGKVA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)