TopFIND 4.0

P48454: Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

General Information

Protein names
- Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
- 3.1.3.16 {ECO:0000269|PubMed:19154138}
- CAM-PRP catalytic subunit
- Calcineurin, testis-specific catalytic subunit
- Calmodulin-dependent calcineurin A subunit gamma isoform
Gene names PPP3CC
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P48454

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSGRRFHLST TDRVIKAVPF PPTQRLTFKE VFENGKPKVD VLKNHLVKEG RLEEEVALKI 
        70         80         90        100        110        120 
INDGAAILRQ EKTMIEVDAP ITVCGDIHGQ FFDLMKLFEV GGSPSNTRYL FLGDYVDRGY 
       130        140        150        160        170        180 
FSIECVLYLW SLKINHPKTL FLLRGNHECR HLTDYFTFKQ ECRIKYSEQV YDACMETFDC 
       190        200        210        220        230        240 
LPLAALLNQQ FLCVHGGMSP EITSLDDIRK LDRFTEPPAF GPVCDLLWSD PSEDYGNEKT 
       250        260        270        280        290        300 
LEHYTHNTVR GCSYFYSYPA VCEFLQNNNL LSIIRAHEAQ DAGYRMYRKS QATGFPSLIT 
       310        320        330        340        350        360 
IFSAPNYLDV YNNKAAVLKY ENNVMNIRQF NCSPHPYWLP NFMDVFTWSL PFVGEKVTEM 
       370        380        390        400        410        420 
LVNVLNICSD DELISDDEAE GSTTVRKEII RNKIRAIGKM ARVFSILRQE SESVLTLKGL 
       430        440        450        460        470        480 
TPTGTLPLGV LSGGKQTIET ATVEAVEARE AIRGFSLQHK IRSFEEARGL DRINERMPPR 
       490        500        510    
KDSIHAGGPM KSVTSAHSHA AHRSDQGKKA HS

Isoforms

- Isoform 2 of Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform - Isoform 3 of Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

Sequence View

        10         20         30         40         50         60 
MSGRRFHLST TDRVIKAVPF PPTQRLTFKE VFENGKPKVD VLKNHLVKEG RLEEEVALKI 
        70         80         90        100        110        120 
INDGAAILRQ EKTMIEVDAP ITVCGDIHGQ FFDLMKLFEV GGSPSNTRYL FLGDYVDRGY 
       130        140        150        160        170        180 
FSIECVLYLW SLKINHPKTL FLLRGNHECR HLTDYFTFKQ ECRIKYSEQV YDACMETFDC 
       190        200        210        220        230        240 
LPLAALLNQQ FLCVHGGMSP EITSLDDIRK LDRFTEPPAF GPVCDLLWSD PSEDYGNEKT 
       250        260        270        280        290        300 
LEHYTHNTVR GCSYFYSYPA VCEFLQNNNL LSIIRAHEAQ DAGYRMYRKS QATGFPSLIT 
       310        320        330        340        350        360 
IFSAPNYLDV YNNKAAVLKY ENNVMNIRQF NCSPHPYWLP NFMDVFTWSL PFVGEKVTEM 
       370        380        390        400        410        420 
LVNVLNICSD DELISDDEAE GSTTVRKEII RNKIRAIGKM ARVFSILRQE SESVLTLKGL 
       430        440        450        460        470        480 
TPTGTLPLGV LSGGKQTIET ATVEAVEARE AIRGFSLQHK IRSFEEARGL DRINERMPPR 
       490        500        510    
KDSIHAGGPM KSVTSAHSHA AHRSDQGKKA HS         10         20         30         40         50         60 
MSGRRFHLST TDRVIKAVPF PPTQRLTFKE VFENGKPKVD VLKNHLVKEG RLEEEVALKI 
        70         80         90        100        110        120 
INDGAAILRQ EKTMIEVDAP ITVCGDIHGQ FFDLMKLFEV GGSPSNTRYL FLGDYVDRGY 
       130        140        150        160        170        180 
FSIECVLYLW SLKINHPKTL FLLRGNHECR HLTDYFTFKQ ECRIKYSEQV YDACMETFDC 
       190        200        210        220        230        240 
LPLAALLNQQ FLCVHGGMSP EITSLDDIRK LDRFTEPPAF GPVCDLLWSD PSEDYGNEKT 
       250        260        270        280        290        300 
LEHYTHNTVR GCSYFYSYPA VCEFLQNNNL LSIIRAHEAQ DAGYRMYRKS QATGFPSLIT 
       310        320        330        340        350        360 
IFSAPNYLDV YNNKAAVLKY ENNVMNIRQF NCSPHPYWLP NFMDVFTWSL PFVGEKVTEM 
       370        380        390        400        410        420 
LVNVLNICSD DELISDDEAE GSTTVRKEII RNKIRAIGKM ARVFSILRQE SESVLTLKGL 
       430        440        450        460        470        480 
TPTGTLPLGV LSGGKQTIET ATVEAVEARE AIRGFSLQHK IRSFEEARGL DRINERMPPR 
       490        500        510    
KDSIHAGGPM KSVTSAHSHA AHRSDQGKKA HS



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P48454-1-unknown MSGRRF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P48454-1-unknown MSGRRF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt85859
    P48454-1-unknown MSGRRF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt85860

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)